研究のタイプ: 医学/生物学の研究 (experimental study)

[ラットのTSHおよび甲状腺ホルモンに対する900 MHz電磁界の影響] med./bio.

Effects of 900MHz electromagnetic field on TSH and thyroid hormones in rats.

掲載誌: Toxicol Lett 2005; 157 (3): 257-262

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研究目的(著者による)

To study whether the serum TSH (thyroid stimulating hormone) and T3 (triiodothronine)-T4 (thyroxine) hormone levels of adult male rats could be altered after exposure to 900 MHz GSM-like electromagnetic field generator.

詳細情報

Thyroid activity is regulated by the thyroid stimulating hormone (TSH) (secreted by pituitary). Elevated TSH levels induce the thyroid to elaborate triiodothronine (T3) and thyroxine (T4).
Animals were maintained under a 12 h light/12 h dark cycle and grouped as follows: control group (without stress and electromagnetic field), sham-exposed group and a 900 MHz group.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: CW
ばく露時間: repeated daily exposure, 30 min/day, 5 days/week for 4 weeks

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 repeated daily exposure, 30 min/day, 5 days/week for 4 weeks
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
チャンバの詳細 A special exposure device with five exposure antennas was used. One exposure system consisted of a ventilated round plastic tube cage (12 cm long x 5.5 cm in diameter) and a half-wave dipole antenna.
ばく露装置の詳細 The whole body of the rat was positioned in close contact above the antenna.
Additional information Rats were allocated to three groups: exposed to EMF, sham-exposed, and control (without stress and EMF).
パラメータ
測定量 種別 Method Mass 備考
電力密度 1 mW/cm² mean 測定値 - ± 0.4 mW/cm²
SAR 2 W/kg peak - - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

TSH values and T3-T4 at the 900MHz exposure group were significantly lower than the sham-exposed group. There were no statistically significant differences in serum TSH values and T3-T4 hormone contents between the control and the sham-exposed group.
These data indicate that 900MHz electromagnetic field emitted by cellular phones decrease serum TSH and T3-T4 levels. This result may be possibly the result of tissue heating. Further investigations are needed in order to clearly show that the degree of TSH and thyroid hormones suppression by radiofrequency electromagnetic field.

研究の種別:

研究助成

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