研究のタイプ: 医学/生物学の研究 (experimental study)

[神経損傷マウスおよび健常マウスにおける脳起電性に対する高周波電磁界への全身ばく露の影響] med./bio.

Effect of whole-body exposure to high-frequency electromagnetic field on the brain electrogeny in neurodefective and healthy mice.

掲載誌: Prague Med Rep 2005; 106 (1): 91-100

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研究目的(著者による)

An electrophysiological investigation of the influence of radiofrequency electromagnetic fields on brain functions in Lurcher mutant mice, which represent a model of neurodegenerative disease, and on healthy control mice.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 880–890 MHz
ばく露時間: see add. information

General information

All experiments were performed under urethane anaesthesia.

ばく露1

主たる特性
周波数 880–890 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 see add. information
ばく露装置
ばく露の発生源/構造
チャンバの詳細 Faraday chamber
ばく露装置の詳細 The EMF was directed by a waveguide with an orifice area of 600 cm² to the space where the animals were placed (modified stereotaxic frame).
Sham exposure A sham exposure was conducted.
Additional information Spontaneous electrocorticogram was measured as 2 min segments from continuously recorded activity either with or without RF EMF exposure. Recording time for each animal was approx. 40 min. The actual duration of exposure is not clear.
パラメータ
測定量 種別 Method Mass 備考
電力 10 W unspecified 指定なし - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中

研究の主なアウトカム(著者による)

Spontaneous electrocorticogram evaluation showed a distinct shift to lower frequency components but clear effect has been found only in wild type mice whereas in Lurcher mutant mice only gentle differences between frequency spectra were revealed. Measurement of hippocampal rhythmicity showed gentle changes with increase of higher frequencies (i.e. opposite effect than in cortex) and changes in theta oscillations registered from a dentate gyrus and CA1 area in both types of animals (wild type and mutant).
These data support the idea about possible influencing the central nervous system by radiofrequency electromagnetic field exposure.

研究の種別:

研究助成

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