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This study was conducted to evaluate the effects of pulsed microwaves exposure on isolated hearts of chicken embryos for two different physiological conditions: regular and irregular heartbeat.
The experiments were carried out on isolated living hearts of 8-9 days old chicken embryos.
Modulation type: pulsed
ばく露時間: repeated exposures in the order of 1 min
|ばく露時間||repeated exposures in the order of 1 min|
|Duty cycle||10 %|
pulse rates of 1-3 Hz
|チャンバの詳細||A pre-oxygenated avian Ringer's solution kept at 37°C was perfused in the sample holder.|
|ばく露装置の詳細||The heart was placed in the sample holder with its main axis perpendicular to the EF in the max. field area and irradiated from the bottom by a tapered open coaxial section.|
|Additional information||In cases of regular heartbeat, the MW pulse rate was set a little higher than the unperturbed natural heart rate. In cases of arrhythmia, a constant pulse rate was selected within physiological limits (1-3 Hz). Usually, the beating heart allowed to conduct tests for about 6 h.|
An appropriate pulse repetition rate caused regularization of irregular heartbeat. During regular heartbeat, an increase of pulse repetition rate similarly increased the heartbeat frequency, until an irregular heartbeat appeared. By applying microwaves, when an arrhythmia occured, a regular heartbeat appeared after a few seconds.
These results suggest a mechanism for the synchronization effect induced by pulse-modulated microwaves on heart cells.