【背景】ミリ波の民需および軍需利用の増加につれて、ミリ波への過剰なばく露の可能性も増すであろう。【目的】35GHzミリ波によって引き起こされるストレス反応の評価。方法：35GHzミリ波の過剰ばく露をSprague-Dawley（SD）系ラットに与え、ラットに生じるストレス反応を脳電図（EEG）変化の解析により定量的に調べた。ストレス反応指標を引き出すために、EEGの平均エネルギーおよびウェーブレット分解系列の相対的変化を用いた。35GHzミリ波は、0.5 W/ cm2 から7.5 W/ cm2 までの平均入射電力密度で与え、ラットのストレス反応と照射量との関係を調べた。照射により誘発されるストレス反応の期間はEEGから定量的に評価した。結果：ストレス反応は、照射の初めの部分での方が後半の部分でよりも強いことが示された。ミリ波照射による皮膚温上昇が、ストレス反応および皮膚の傷害の主な原因である。予測通り、照射レベルが高くなると、反応時間は減少し、反応強度は増大した。
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To study the stress reactions in rats evoked by over-exposure to 35 GHz millimeter waves.
24 rats were divided into eight groups (according to the power flux densities; each group n=3) and skin temperature of the shaved back was measured before, during and after exposure under anaesthesia. Additionally, 48 rats with implanted electrodes were divided into eight groups (each group n=6) and exposed in restrained position.
Modulation type: pulsed
ばく露時間: continuous for 30 s
Rats were divided into eight groups: i) exposure to 0.5 W/cm² over an area of 3.6 cm² ii) exposure to 0.9 W/cm² over an area of 3.6 cm² iii) exposure to 1.2 W/cm² over an area of 3.6 cm² iv) exposure to 1.5 W/cm² over an area of 3.6 cm² v) exposure to 1.5 W/cm² over an area of 1.8 cm² vi) exposure to 3.5 W/cm² over an area of 1.8 cm² vii) exposure to 5.0 W/cm² over an area of 1.8 cm² viii) exposure to 7.5 W/cm² over an area of 1.8 cm²
|ばく露時間||continuous for 30 s|
|Pulse width||1 µs|
two pulse trains were employed: a) 500 pulses/s b) 1000 pulses/s
|チャンバの詳細||screened exposure chamber with the antenna inside the chamber|
|ばく露装置の詳細||exposure beam directed to the rat's back; for EEG recording rat fixed by rubberized fabrics on a plastic board on the object stage of the exposure chamber; for temperature measurments rats anaesthetized|
|Sham exposure||A sham exposure was conducted.|
|電力密度||0.5 W/cm²||-||-||-||for an exposure area of 3.6 cm²|
|電力密度||1.2 W/cm²||-||-||-||for an exposure area of 3.6 cm²|
|電力密度||0.9 W/cm²||-||-||-||for an exposure area of 3.6 cm²|
|電力密度||1.5 W/cm²||-||-||-||for an exposure area of 3.6 cm²|
|電力密度||1.5 W/cm²||-||-||-||for an exposure area of 1.8 cm²|
|電力密度||3.5 W/cm²||-||-||-||for an exposure area of 1.8 cm²|
|電力密度||5 W/cm²||-||-||-||for an exposure area of 1.8 cm²|
|電力密度||7.5 W/cm²||-||-||-||for an exposure area of 1.8 cm²|
The data showed that stress reactions (indicated by EEG analysis) are more intense during the first part of the irradiation than during the later part: stress reactions began at the first second and the intensities of stress reactions were much higher during the 1st-17th s than during the 17th-30th s. The skin temperature increase (thermal pain) produced by millimeter wave exposure was the principle reason for stress reactions. As expected, at the higher levels of irradiation, the stress reaction time decreased and the stress reaction intensity increased.