疫学研究 (observational study)

[妊娠中の携帯電話の使用と自然流産のリスク] epidem.

Use of mobile phone during pregnancy and the risk of spontaneous abortion

著者: Mahmoudabadi FS, Ziaei S, Firoozabadi M, Kazemnejad A

掲載誌: J Environ Health Sci Eng 2015; 13: 34

この研究は、妊娠＜14週で原因不明の自然流産をした女性292人と妊娠中（＞14週）の女性308人を対象にした症例対照研究である。質問票により、社会経済的状態、肥満、医学的および出産履歴、生活スタイル、妊娠中の携帯電話使用について調査した。携帯電話使用に関しては、1日当たりの平均通話時間、不使用時の置き場所、ハンズフリー機器の使用、携帯電話の通話以外のアプリの使用、メーカ表示のSAR値、有効SARの平均値（1日当たりの平均通話時間×SAR）を考慮した。その結果、ハンズフリー機器の使用以外の全ての携帯電話関連項目について両群に有意差が見られた、と報告している。

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研究の目的(著者による)

A case-control study was conducted in Iran to determine the effects of exposure to mobile phones during pregnancy and the risk of spontaneous abortion.

影響評価項目／リスク推定のタイプ

生殖への影響および妊娠アウトカム: spontaneous abortion

リスク推定のタイプ:

発生率

ばく露

- 移動体通信システム
- 携帯電話

ばく露評価

質問票: average calling time per day based on bills, location of mobile phone when not in use (in handbags, clothing pockets, ≥ 60-70 cm away from the body), use of hands-free equipment, use of phones for other applications (to send messages, to listen to music, and to play games)
計算: effective SAR calculated as average duration of calling time per day multiplied with SAR reported by the manufacturer

調査対象集団

グループ:
- 女性
- 子宮内の胎児
年齢: 18–35年
観察期間: not stated
調査地域: Iran (Tehran)

症例集団

特性: women with unexplained spontaneous abortion at < 14 weeks gestation, singleton pregnancy, spontaneous pregnancy without the use of assisted reproductive technology
データ源: 10 hospitals
排除クライテリア: chronic diseases, genetic disorder, history of birth defects in previous pregnancies; cigarette smoking, alcohol or any drug consumptions

対照集団

排除クライテリア: vaginal bleeding in the first trimester of pregnancy

調査規模

	症例	対照
適格者	292	308
評価可能	226	246

統計学的分析方法:

ロジスティック回帰
カイ二乗検定
t-test

(調整:

maternal age, paternal age, history of abortion and family relationship

)

結論(著者による)

All data pertaining to mobile phone use such as average calling time per day, the location of the mobile phones when not in use, use of phones for other applications, SAR and the average of the calculated effective SAR, except the use of hands-free devices were different between the case group and the control group. A significant association between the calculated effective SAR and the risk of spontaneous abortions was observed (OR 1.11; CI 1.07-1.16).
The results suggest that use of mobile phones could be related to the early spontaneous abortions.

研究の限界(著者による)

The results should be interpreted with cautions due to study design, further not considered risk factors for spontaneous abortion and exposure assessment.

研究助成

Tarbiat Modares University, Tehran, Iran