研究のタイプ: 医学/生物学の研究 (experimental study)

Urinary 6-Sulphatoxymelatonin Excretion of Rats is not Changed by 24 Hours of Exposure to A Horizontal 50-Hz, 100-μT Magnetic Field. med./bio.

掲載誌: Electro Magnetobiol 1999; 18 (1): 23-31

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研究目的(著者による)

The effects of exposure of rats to a 50 Hz magnetic field on melatonin production should be investigated.

詳細情報

The rats were divided into the following groups: 1) exposure to a 50 Hz magnetic field with 1 µT perpendicular to the north pole of the earth's magnetic field (n=6), 2) exposure to 1 µT parallel to the north pole (n=5), 3) exposure to 100 µT perpendicular to the north pole (n=6), 4) exposure to 100 µT parallel to the north pole (n=5).
The rats were examined for 5 days and urine was collected every night. For the first 2 days, the rats were kept in their cages without exposure to the magnetic field. The urine samples collected there were used as controls. On the 3rd day, the rats were exposed and afterwards examined for further 2 days without exposure.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 50 Hz
ばく露時間: 24 hours
ばく露2: 50 Hz
ばく露時間: 24 hours

ばく露1

主たる特性
周波数 50 Hz
タイプ
  • magnetic field
波形
  • sinusoidal
ばく露時間 24 hours
ばく露装置
ばく露の発生源/構造
チャンバの詳細 rats were kept individually in metabolic cages, which were able to separate the urine from feces, food, and hair; the inner diameter of the cages was 20 cm; the height was 11 cm; the cages were made of plexiglass and glass, only the feeders were made of nonferrous stainless steel
ばく露装置の詳細 pair of double-wound coils embedded in molded epoxy resin to avoid vibration; the inner diameter of the coils was 42 cm; the distance between the two parallel, vertially mounted coils was 35 cm; the orientation of the magnetic field was horizontal; one of two animal cages was placed into the center of the coils, where flux density was 100 µT; the inhomogeneity of the magnetic field was less than 4% inside the cage; the perturbation around or in the stainless
steel feeder was less than 1%; the stray field in the other cage located 1.1 m away from the coils was 1 µT; the temperature increase of the coils was below 1°C during exposure; the geomagnetic field was 48 µT in the laboratory
パラメータ
測定量 種別 Method Mass 備考
磁束密度 1 µT effective value 測定値 - ± 0.1 µT

ばく露2

主たる特性
周波数 50 Hz
タイプ
  • magnetic field
波形
  • sinusoidal
ばく露時間 24 hours
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
磁束密度 100 µT effective value 測定値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露前
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

No significant differences were found in the concentration of 6-sulfatoxy melatonin in urine during and after magnetic field exposure compared to before exposure.
The authors conclude that no effects of exposure of rats to a 50 Hz magnetic field on melatonin production could be found.

研究の種別:

研究助成

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