研究のタイプ: 医学/生物学の研究 (experimental study)

[蝸牛受容体へのマイクロ波(900MHz)の影響:ばく露装置と予備的結果] med./bio.

Effects of microwaves (900 MHz) on the cochlear receptor: exposure systems and preliminary results.

掲載誌: Radiat Environ Biophys 2000; 39 (2): 131-136

この研究は、マイクロ波(900MHz)ばく露によりラット蝸牛上皮に生じる音響的な耳の機能への影響の可能性を調べた。そのための実験装置を開発し、聴覚損傷との客観的で器質的な相関を探求した。雄のSprague-Dawleyラットを用い、立方体チャンバー内での遠方界ばく露による2つのSARで実験を行なった。結果として、2つのSARのどちらにおいても、統計的に有意な証拠は得られなかった;ばく露装置および診断装置は、聴覚系への潜在的な影響の研究に極めて有用であったが、これらの実験で採用されたパラメータについて、証拠は観察されなかった、と報告している。

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研究目的(著者による)

To assess potential changes occuring in the cochlear receptor after exposure to electromagnetic fields of a given frequency (around 900 MHz) and a low intensity.

詳細情報

A cubic chamber was developed and a routine acoustic apparatus employed to observe otofunctional effects. In this paper, the methodological approach and the experimental set-up are described, and the first preliminary results of the cochlear receptor functionality are reported.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 950 MHz
Modulation type: CW
ばく露時間: repeated daily exposure, 3 h/day, for 3 days
  • 電力密度: 4.58 W/m² unspecified
  • SAR: 0.2 W/kg mean (unspecified) (max. 0.32 W/kg)
  • 電力密度: 23 W/m² unspecified
  • SAR: 1 W/kg mean (unspecified) (max. 1.6 W/kg)
ばく露2: 936 MHz
Modulation type: CW
ばく露時間: repeated daily exposure, 3 h/day, for 5 days

ばく露1

主たる特性
周波数 950 MHz
タイプ
  • electromagnetic field
特性
  • far field
ばく露時間 repeated daily exposure, 3 h/day, for 3 days
Additional information vertical polarisation
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
  • 無響室
  • double-ridged waveguide horn antenna (D = 24 cm, gain = 3.67)
Distance between exposed object and exposure source 65 cm
チャンバの詳細 cubic chamber (side 1.2 m) shielded with copper sheets and lined with RF absorbing material (-20 dB)
ばく露装置の詳細 Eight rats immobilised in cylindrical (D=4.5 cm, L=12 cm) Lucite jigs, ending with a cone, were positioned with their heads facing the mouth of the antenna at 65 cm and their longitudinal axis oriented along the direction of propagation. There were two arrays of four jigs at 50 and 60 cm from the ground over an acrylic support.
Sham exposure A sham exposure was conducted.
Additional information Fiberoptic thermosensors were placed on the skin of one rat in the jig during the first day of exposure to monitor any change of temperature.
パラメータ
測定量 種別 Method Mass 備考
電力密度 4.58 W/m² unspecified 測定値 - -
SAR 0.2 W/kg mean 測定値および計算値 unspecified max. 0.32 W/kg
電力密度 23 W/m² unspecified 測定値 - -
SAR 1 W/kg mean 測定値および計算値 unspecified max. 1.6 W/kg

ばく露2

主たる特性
周波数 936 MHz
タイプ
  • electromagnetic field
特性
  • far field
ばく露時間 repeated daily exposure, 3 h/day, for 5 days
Additional information vertical polarisation
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
Distance between exposed object and exposure source 65 cm
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
電力密度 23 W/m² unspecified 測定値 - -
SAR 1 W/kg mean 測定値および計算値 unspecified -

Reference articles

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
  • 感覚器
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The exposure system and the diagnostic apparatus are extremely useful to investigate a potential effect on the auditory system. However, with the parameters applied in these experiments, no evidence for a biological effect was observed.

研究の種別:

研究助成

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