研究のタイプ: 医学/生物学の研究 (observational study)

[磁界とメラトニン仮説:50 Hz磁界へ慢性的に曝されている作業員での研究] med./bio.

Magnetic fields and the melatonin hypothesis: a study of workers chronically exposed to 50-Hz magnetic fields.

掲載誌: Am J Physiol Regul Integr Comp Physiol 2003; 284 (6): R1529-R1535

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研究目的(著者による)

To investigate the potential effect of occupational and residential exposure to 50 Hz magnetic fields on the secretion of melatonin in men.

詳細情報

Thirty male subjects participated in the study. Out of these, 15 were exposed to 50 Hz magnetic fields during worktime (in electrical substation) and free-time (living near the substation). The other 15 subjects had non-technical jobs and were subjected only to the normal electric and magnetic fields of daily environment.
Occurring magnetic fields were measured for each subject for one week with a wearable measurement device during normal activities. To determine the melatonin level in blood, subjects stayed in a hospital for one night. A catheter was inserted to collect blood samples hourly without waking. Additionally urine was collected to determine the 6-sulphatoxy melatonin level.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 50 Hz
ばく露時間: 1 - 20 years
exposed subjects
ばく露2: 50 Hz
control subjects

ばく露1

主たる特性
周波数 50 Hz
タイプ
  • magnetic field
ばく露時間 1 - 20 years
Additional information exposed subjects
ばく露装置
ばく露の発生源/構造
  • occupational and residential exposure (electrical substation)
パラメータ
測定量 種別 Method Mass 備考
磁束密度 2.6 µT mean 測定値 - -
磁束密度 0.1 µT mean 測定値 - -
磁束密度 0.64 µT mean 測定値 - -
磁束密度 0.82 µT mean 測定値 - -
磁束密度 0.72 µT mean 測定値 - -

ばく露2

主たる特性
周波数 50 Hz
タイプ
  • magnetic field
Additional information control subjects
ばく露装置
ばく露の発生源/構造
  • everyday exposure
パラメータ
測定量 種別 Method Mass 備考
磁束密度 0.092 µT mean 測定値 - -
磁束密度 0.004 µT mean 測定値 - -
磁束密度 0.04 µT mean 測定値 - -
磁束密度 0.04 µT mean 測定値 - -
磁束密度 0.04 µT mean 測定値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

No significant differences in the melatonin level as well as in the 6-sulphatoxy melatonin level were found between exposed subjects and the control group.
The authors conclude that occupational and residential exposure to 50 Hz magnetic fields do not lead to alterations in the melatonin secretion.

研究の種別:

研究助成

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