Study type: Medical/biological study (experimental study)

Proteomics analysis of human endothelial cell line EA.hy926 after exposure to GSM 900 radiation. med./bio.

Published in: Proteomics 2004; 4 (5): 1359-1365

Aim of study (acc. to editor)

To study the effect of mobile phone irradiation (900 MHz, GSM) on protein expression in the endothelial cell line EA.hy926.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 1 h

Exposure 1

Main characteristics
Frequency 900 MHz
Exposure duration continuous for 1 h
Modulation
Modulation type pulsed
Exposure setup
Exposure source
  • see reference article
Setup Cells were exposed in glass Petri dishes of 5 cm diameter.
Additional info Control cells were sham-exposed in the same exposure chamber.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2.4 W/kg mean unspecified unspecified -

Reference articles

  • Leszczynski D et al. (2002): Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: Molecular mechanism for cancer- and blood-brain barrier-related effects.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Up to 38 various proteins have statistically significantly altered their expression levels following exposure. Two of the affected proteins were determined to be isoforms of cytoskeletal vimentin. Changes in vimentin expression suggest that some form of cytoskeleton-related response might take place in cells exposed to the mobile phone irradiation.

Study character:

Study funded by

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