研究のタイプ: 医学/生物学の研究 (experimental study)

[ヌードマウスの皮膚に対するGMS900, 800信号の影響 I 2時間急性ばく露] med./bio.

Effect of GSM-900 and -1800 signals on the skin of hairless rats. I: 2-hour acute exposures.

掲載誌: Int J Radiat Biol 2006; 82 (9): 669-674

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研究目的(著者による)

To study whether the cells of hairless rat skin are affected by acute local exposure to GSM-900 or -1800 radiofrequency irradiation.

詳細情報

To perform positive controls rats were exposed to UV-B radiation.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 2 h
  • SAR: 5.8 W/kg mean (± 0.4 W/kg at 1 mm depth)
ばく露2: 1,800 MHz
Modulation type: pulsed
ばく露時間: continuous for 2 h
  • SAR: 4.8 W/kg mean (± 0.4 W/kg at 1 mm depth)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 2 h
Modulation
Modulation type pulsed
ばく露装置
ばく露の発生源/構造
  • square loop antenna (1 cm x 3 cm)
ばく露装置の詳細 Animals were restrained in rocket type plastic tubes and exposed using a loop antenna [Leveque et al., 2004] located on the right side of the back.
Sham exposure A sham exposure was conducted.
Additional information For positive control, two rats were exposed to UVB irradiation (400 mJ/cm²).
パラメータ
測定量 種別 Method Mass 備考
SAR 5.8 W/kg mean 推定値 - ± 0.4 W/kg at 1 mm depth

ばく露2

主たる特性
周波数 1,800 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 2 h
Modulation
Modulation type pulsed
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 4.8 W/kg mean 推定値 - ± 0.4 W/kg at 1 mm depth

Reference articles

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
  • 感覚器
  • skin
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

No major histological alterations were found in the studied cellular parameters immediately after the 2 h local exposure to GSM-900- or -1800. No difference in epidermis thickness was detected among the animal groups. Radiofrequency exposure did not affect cell proliferation. Filaggrin, collagen, and elastin were not modified by exposure to GSM-900 or -1800 signals.

研究の種別:

研究助成

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