Study type: Medical/biological study (experimental study)

Evaluation of hormonal change, biochemical parameters, and histopathological status of uterus in rats exposed to 50-Hz electromagnetic field. med./bio.

Published in: Toxicol Ind Health 2009; 25 (3): 153-158

Aim of study (acc. to author)

To investigate the effects of 50 Hz electromagnetic fields on hormonal status and on morphology of the uterus and ovaries of rats.

Background/further details

Female rats were assigned to three exposure groups (each n=7) with one, two and three months exposure duration and a control group (n=7).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 24 h for 1, 2 or 3 months

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 24 h for 1, 2 or 3 months
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 4.821 µT average over time measured - -
electric field strength 1.66 kV/m average over time measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No effects of exposure on progesterone, on 17-beta-estradiol levels, or on the morphology and weight of the uterus and ovaries were found.
Depending on exposure duration significant reductions in catalase enzyme activity were found. The most reduced catalase enzyme activities were observed in the three-months exposure group. For glutathione and malondialdehyde no significant differences between groups were found.

Study character:

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