研究のタイプ: 医学/生物学の研究 (experimental study)

[2450 MHzマイクロ波放射へのラットのインビボ急性ばく露に関する研究:その2 甲状腺および副腎軸ホルモンに対する影響] med./bio.

Studies on acute in vivo exposure of rats to 2450-MHz microwave radiation. II. Effects on thyroid and adrenal axes hormones.

掲載誌: Radiat Res 1981; 88 (3): 448-455

この研究は、ラットへの2450MHz(cw)マイクロ波の8時間連続ばく露の影響を、入射電力密度0、2および10mW / cm 2で調べた。結果として、血清サイロキシン(T4)およびトリヨードチロニン(T3)ならびにT3の取り込み、遊離チロキシン指数など、甲状腺軸機能は、どのばく露条件でも変化しなかった;副腎軸活性も、8時間のマイクロ波ばく露の影響を受けなかった;血清コルチコステロン濃度は、10mW / cm2群では7.8 μg/dl、0または2 mW / cm 2群では9.9 μg/dl、無処置群では7.0 μg/dlであった、と報告している。

The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →

研究目的(acc. to author and editor)

To study the endocrine effects of microwave exposure of rats.

詳細情報

Rats were exposed in vivo, and possible endocrine changes were investigated by determination of several endocrine hormones in blood samples. Investigations were carried out concerning the hormones thyroxine (T4), triiodothyronine (T3), and corticosterone. T4 and T3 are formed and secreted by the thyroid gland, whereas corticosterone is a adrenal cortex product.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 2.45 GHz
Modulation type: CW
ばく露時間: continuous for 8 h

ばく露1

主たる特性
周波数 2.45 GHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 8 h
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
Distance between exposed object and exposure source 1.55 m
チャンバの詳細 chamber 2,5 m x 3,0 m x 2,5 m lined with HPY-18 microwave absorber( -45dB)
ばく露装置の詳細 animals placed in 2.5 cm thick Styrofoam cages (10 cm x 20 cm) positioned inside the chamber
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
電力密度 100 mW/cm² spatial average 測定値 - -
電力密度 2 mW/cm² spatial average 測定値 - -
SAR 0.22 mW/g - - whole body -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The microwave exposure had no effects on the serum concentrations of thyroxine (T4), triiodothyronine (T3) and the uptake of T3. These unaltered hormone concentrations could be interpreted in that way that the thyroid gland was not affected by exposure. The serum concentrations of corticosterone, which is adrenal cortex made, were nonuniform. Low level exposure leads to increased concentration, whereas at high level exposure the corticosterone concentration was similar to the unexposed controles.
These results suggest that the experimental procedure effects the adrenal cortex, and that this effect could be counteracted by high level exposure.

研究の種別:

研究助成

関連論文