研究のタイプ: 医学/生物学の研究 (experimental study)

[GSM900 MHz携帯電話放射はばく露時間に依存してニホンウズラでの初期胚発生を刺激または抑制し得る] med./bio.

GSM 900 MHz cellular phone radiation can either stimulate or depress early embryogenesis in Japanese quails depending on the duration of exposure.

掲載誌: Int J Radiat Biol 2013; 89 (9): 756-763

この研究は、ニホンウズラでの初期胚発生に対するGSM900MHz携帯電話放射の影響を2通りのばく露時間で調べた。卵内の胚には、GSM900MHz信号(平均電力密度0.25 W/cm 2、SAR 3 W/kg)の断続(48秒間のON、12秒間のOFF)を、孵卵器に入れた直後から38時間(n=26;対照群も同数)、あるいは孵卵器に入れる前の120時間と孵卵器内での38時間の計158時間(n=32;対照群も同数)ばく露した。ばく露後、38時間胚の体節の分節数の顕微鏡観察、ならびにDNA損傷のアルカリコメットアッセイを行った。その結果、38時間ばく露では体節の分節数が増加し、158時間ばく露では減少した;38時間胚の細胞のDNA鎖切断のレベルは、それぞれの対照群に比較して、38時間ばく露では低下し、158時間ばく露では上昇した、と報告している。

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研究目的(著者による)

To examine the effects of mobile phone-exposure (GSM) on the early embryogenesis in japanese quails.

詳細情報

Four groups of fertilized eggs were examined (n=10-12 per group): 1.) control group, 38 h brooding, 2.) exposed during 38 h brooding, 3.) control group, 120 h at room temperature, then 38 h brooding (158 h in total) and 4.) exposed during 120 h at room temperature, then during 38 h brooding (158 h in total). Brooding took place in incubators (38°C). Control groups and exposure groups were brooded at the same time, however the control eggs were shielded against the electromagnetic fields by 6 layers of aluminium foil.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 890–915 Hz
ばく露時間: intermittent for 38 h: 48 sec "on" (speech mode), 12 sec "off"
ばく露2: 890–915 MHz
ばく露時間: intermittent for 158 h (120 h before and 38 h during brooding): 48 sec "on" (speech mode), 12 sec "off"

ばく露1

主たる特性
周波数 890–915 Hz
タイプ
  • electromagnetic field
ばく露時間 intermittent for 38 h: 48 sec "on" (speech mode), 12 sec "off"
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
  • Nokia 3120 GSM mobile phone
チャンバの詳細 laboratory incubator (metal covers from the door and the sides removed and replaced by plastic covers); temperature 38.3±0.2°C, relative humidity 60%
ばく露装置の詳細 eggs placed on horizontal trays; cell phone positioned on a plastic stand inside the incubator at a distance of 3 cm from the eggs; unexposed eggs placed inside the same incubator at a distance of 10 cm from the exposed eggs and shielded by 6 layer of an aluminum foil (each foil was 0.03 mm thick); cell phone kept in connecting mode by auto-redial; each connecting attempt lasted 48 s; distance between the phone and the eggs: 3 cm - 10 cm
パラメータ
測定量 種別 Method Mass 備考
電力密度 2.5 mW/m² mean - - on the egg surface
電界強度 0.02 V/m - 計算値 - inside the egg
SAR 3 µW/kg - 計算値 - -

ばく露2

主たる特性
周波数 890–915 MHz
ばく露時間 intermittent for 158 h (120 h before and 38 h during brooding): 48 sec "on" (speech mode), 12 sec "off"
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
  • E1と同じ装置
  • Nokia 3120 GSM mobile phone
ばく露装置の詳細 exposure during the first 120 h on a lab bench at room temperature
パラメータ
測定量 種別 Method Mass 備考
電力密度 2.5 mW/m² mean - - on the egg surface
電界強度 0.02 V/m - 計算値 - inside the egg
SAR 3 µW/kg - 計算値 - -

Reference articles

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:

研究の主なアウトカム(著者による)

No malformations in the embryos occurred and no differences in the surface temperature of the eggs were found between the groups.
In the 38 hours-exposed group, a significant increased number of differentiated somites was observed in comparison to the corresponding control group. Additionally, DNA strand breaks were significantly decreased compared to the control group. An exposure for 158 hours significantly decreased the number of differentiated somites and resulted in a significant increase of DNA strand breaks compared to the control group.
The authors conclude that mobile phone-exposure can stimulate or depress the embryogenesis of Japanese quails and that this effect could depend on the exposure duration.

研究の種別:

研究助成

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