研究のタイプ: 医学／生物学の研究 (experimental study)

[無線装置からの電磁界ばく露に対する線虫の応答] med./bio.

Response of Caenorhabditis elegans to wireless devices radiation exposure

著者: Fasseas MK, Fragopoulou AF, Manta AK, Skouroliakou A, Vekrellis K, Margaritis LH, Syntichaki P
掲載誌: Int J Radiat Biol 2015; 91 (3): 286-293
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この研究は、GSM携帯電話・Wi-Fiルータ・DECT無線式電話などの無線装置から放射される電磁界（電界レベルでICNIRPガイドライン値を下回る）を様々なばく露時間で与えた線虫（Caenorhabditis elegans）における影響を調べた。線虫は、様々な発達段階での同期集団を用いた。また、野生タイプ、加齢高感受性変異タイプ、ストレス高感受性変異タイプを用いた。結果として、どの実験条件においても、寿命、生殖、成長、記憶、活性化酸素種、アポトーシス、遺伝子発現に、ばく露群と対照群で有意差は見られなかった､と報告している。

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研究目的（著者による）

The effects of exposure of Caenorhabditis elegans to different radio frequency electromagnetic fields (DECT, WiFi, GSM) on growth, fertility, lifespan, chemotaxis, short-term memory and stress should be investigated.

詳細情報

Worms of different strains were distributed in one of the following groups: 1) DECT exposure, 2) DECT sham exposure, 3) WiFi exposure, 4) WiFi sham exposure, 5) GSM exposure and 6) GSM sham exposure. Several tests with different strains (wild type, age- and stress-sensitive strains (DR1572, DR26, TK22 and RB864), model strains for neurodegenerative diseases (NL5901 for Parkinson's disease and CL4176 for Alzheimer's disease) and GFP-transgenic strains (CL2070, CF1553, SJ4005, LG333, LD1171 and CL2166)) were conducted in the groups. All tests were performed at least twice.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 1,880–1,900 MHz
Modulation type: pulsed
ばく露時間: continuous for 0.5, 1, 3, 6 or 24 h
DECT
ばく露2: 2,400–2,480 MHz
Modulation type: pulsed
ばく露時間: continuous for 0.5, 1, 3, 6 or 24 h
ばく露3: 1,780–1,800 MHz
Modulation type: pulsed
ばく露時間: continuous for 0.5, 1 or 3 hours
GSM

ばく露1

主たる特性
周波数 1,880–1,900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 0.5, 1, 3, 6 or 24 h
Additional information DECT
Modulation
Modulation type pulsed
Repetition frequency 100 Hz
ばく露装置
ばく露の発生源／構造
  • DECT wireless phone base
ばく露装置の詳細 plates containing worms were placed next to the operating device at a distance of 5-10 cm; temperature was 20°C
Sham exposure A sham exposure was conducted.
パラメータ
測定量 値 種別 Method Mass 備考
電界強度 3.75 V/m mean 測定値 - -
電界強度 11.3 V/m peak 測定値 - -
Additional parameter details

SAR values were calculated because the dielectric properties and mass density of the nematode were largely unknown and because it is more likely that the electromagnetic field is not uniform within the culture plates; electrical field intensity of background radiofrequency exposure was below 0.2 V/m; background extremely low frequency magnetic field was 200 nT

ばく露2

主たる特性
周波数 2,400–2,480 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 0.5, 1, 3, 6 or 24 h
Additional information WiFi
Modulation
Modulation type pulsed
Repetition frequency 10 Hz
ばく露装置
ばく露の発生源／構造
ばく露装置の詳細 plates containing worms were placed next to the operating device at a distance of 5-10 cm; temperature was 20°C
Sham exposure A sham exposure was conducted.
パラメータ
測定量 値 種別 Method Mass 備考
電界強度 2.1 V/m mean 測定値 - -
電界強度 9.7 V/m peak 測定値 - -
Additional parameter details

SAR values were calculated because the dielectric properties and mass density of the nematode were largely unknown and because it is more likely that the electromagnetic field is not uniform within the culture plates; electrical field intensity of background radiofrequency exposure was below 0.2 V/m; background extremely low frequency magnetic field was 200 nT

ばく露3

主たる特性
周波数 1,780–1,800 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 0.5, 1 or 3 hours
Additional information GSM
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源／構造
  • セルラ－電話
ばく露装置の詳細 plates containing worms were placed next to the operating device at a distance of 5-10 cm; temperature was 20°C
Sham exposure A sham exposure was conducted.
パラメータ
測定量 値 種別 Method Mass 備考
電界強度 5.53 V/m average over time 測定値 - -
電界強度 15.4 V/m peak 測定値 - -
磁束密度 50 nT - 測定値 - magnetic flux density of 217 Hz GSM modulation
Additional parameter details

SAR values were calculated because the dielectric properties and mass density of the nematode were largely unknown and because it is more likely that the electromagnetic field is not uniform within the culture plates; electrical field intensity of background radiofrequency exposure was below 0.2 V/m; background extremely low frequency magnetic field was 200 nT

Reference articles

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム（著者による）

No significant differences were found between the exposed groups 1, 3 and 5 and sham exposed groups 2, 4 and 6, respectively, in any test.
The authors conclude that an exposure of Caenorhabditis elegans to radio frequency electromagnetic fields from DECT, WiFi and GSM sources has no effect on the investigated parameters of the study under the given conditions.

研究の種別:

研究助成

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