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The effects of exposure of rats to a 900 MHz electromagnetic field on the properties of bones and on bone metabolism parameters in the blood should be investigated.
20 rats were divided into the following groups (n=10 each): 1) exposure and 2) sham exposure.
|ばく露時間||intermittent for 15 seconds every 30 minutes, 16 times/day for 28 days|
|チャンバの詳細||plastic cage (56 x 35 cm ground area), rats could move freely|
|ばく露装置の詳細||the mobile phone, operating in silent mode and sending a fax signal to ensure a permanently active sending signal, was placed centrally under the plastic cage at a distance of 4 cm|
|Sham exposure||A sham exposure was conducted.|
|Additional information||sham exposure group was sham exposed for 22 h/day|
No significant differences regarding weight and proportions of bones could be detected between the exposure and sham exposure group.
In the tibia, the energy at the maximum bending force was significantly increased in the exposure group compared to the sham exposure group and at the same time, the stress at the maximum bending force and at fracture were significantly reduced. The authors see these results as an indication of a possible lower susceptibility of exposed bones to external forces.
The total and relative amount (ratio to the amount of phosphorus) of calcium was significantly increased in the tibia after exposure compared to the sham exposure group.
The amount of osteocalcin was significantly increased in the blood serum of exposed animals compared to the sham exposure group after 1 week of exposure, as was the amount of pyridinoline after 4 weeks of exposure.
The authors conclude that exposure of rats to a 900 MHz electromagnetic field has no impact on the macrometrical properties of bones but could alter mineralization and the bone metabolism, which in turn might alter the mechanical bone properties.