研究のタイプ: 医学/生物学の研究 (experimental study)

[ラットの骨格系に対する携帯電話の電磁放射の影響] med./bio.

The influence of electromagnetic radiation generated by a mobile phone on the skeletal system of rats.

掲載誌: Biomed Res Int 2015: 896019

この研究は、雄ラット携帯電話からの900MHz電磁界を28日間ばく露し、骨格系への影響を調べた。検査項目は、巨視的な骨パラメータ、長骨の機械的特性、骨のカルシウムおよびリンの含有量、オステオカルシンおよび骨吸収マーカの血中濃度である。その結果、巨視的な骨パラメータには影響が見られなかったが、その他の検査項目には変化が見られた、と報告している。

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研究目的(著者による)

The effects of exposure of rats to a 900 MHz electromagnetic field on the properties of bones and on bone metabolism parameters in the blood should be investigated.

詳細情報

20 rats were divided into the following groups (n=10 each): 1) exposure and 2) sham exposure.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
ばく露時間: intermittent for 15 seconds every 30 minutes, 16 times/day for 28 days
  • 電力密度: 85.3 µW/m² spatial average (while establishing connection)
  • 電力密度: 17 µW/m² spatial average (during active connection)
  • SAR: 0.69 W/kg maximum (according to manufacturer)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
特性
  • far field
ばく露時間 intermittent for 15 seconds every 30 minutes, 16 times/day for 28 days
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
  • Nokia 5110
チャンバの詳細 plastic cage (56 x 35 cm ground area), rats could move freely
ばく露装置の詳細 the mobile phone, operating in silent mode and sending a fax signal to ensure a permanently active sending signal, was placed centrally under the plastic cage at a distance of 4 cm
Sham exposure A sham exposure was conducted.
Additional information sham exposure group was sham exposed for 22 h/day
パラメータ
測定量 種別 Method Mass 備考
電力密度 85.3 µW/m² spatial average 測定値および計算値 - while establishing connection
電力密度 17 µW/m² spatial average 測定値および計算値 - during active connection
SAR 0.69 W/kg maximum - - according to manufacturer

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露前
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

No significant differences regarding weight and proportions of bones could be detected between the exposure and sham exposure group.
In the tibia, the energy at the maximum bending force was significantly increased in the exposure group compared to the sham exposure group and at the same time, the stress at the maximum bending force and at fracture were significantly reduced. The authors see these results as an indication of a possible lower susceptibility of exposed bones to external forces.
The total and relative amount (ratio to the amount of phosphorus) of calcium was significantly increased in the tibia after exposure compared to the sham exposure group.
The amount of osteocalcin was significantly increased in the blood serum of exposed animals compared to the sham exposure group after 1 week of exposure, as was the amount of pyridinoline after 4 weeks of exposure.
The authors conclude that exposure of rats to a 900 MHz electromagnetic field has no impact on the macrometrical properties of bones but could alter mineralization and the bone metabolism, which in turn might alter the mechanical bone properties.

研究の種別:

研究助成

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