研究のタイプ: 医学/生物学の研究 (experimental study)

[1,800 MHzのグローバル移動通信システムからの放射ばく露による、ラットの海馬や大脳皮質における遺伝子発現の変化] med./bio.

Exposure to radiation from global system for mobile communications at 1,800 MHz significantly changes gene expression in rat hippocampus and cortex.

掲載誌: Environmentalist 2008; 28 (4): 458-465

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研究目的(著者による)

To study whether exposure to the irradiation from a GSM mobile phone at 1800 MHz has an effect upon the gene expression pattern in rat brain cortex and hippocampus.

詳細情報

8 male rats were assigned to an exposure group (n=4) and a sham exposure group (n=4). The SAR-level for the brain was with 30 mW/kg below the limit for mobile phone emissions set by ICNIRP.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 1,800 MHz
Modulation type: pulsed
ばく露時間: continuous for 6 h

ばく露1

主たる特性
周波数 1,800 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 6 h
Modulation
Modulation type pulsed
Pulse width 0.57 ms
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源/構造
チャンバの詳細 1000 mm x 1100 mm x 2050 mm anechoic chamber made of six demountable plywood board panels laminated with copper foil and covered with absorbing material on the inside; directional antenna placed in the top part of the chamber
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
電界強度 11.54 V/m - - - -
電力密度 0.35 W/m² - - - -
SAR 13 mW/kg average over mass 計算値 whole body -
SAR 30 mW/kg average over mass 計算値 brain -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The genes did not significantly discriminate between exposed and sham exposed animals. The gene oncology analysis of the differentially expressed genes of both groups revealed four highly significant altered gene categories in both cortex and hippocampus (transmembrane receptor activity, receptor activity, cell surface receptor linked signal transduction and G-protein coupled receptor signaling pathway).
Most of these categories are connected with membrane functions what indicates that the cell membrane is an important target for electromagnetic field effects.

研究の種別:

研究助成

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