研究のタイプ: 医学/生物学の研究 (experimental study)

[妊娠時の磁界ばく露:ラットの松果体と大脳皮質でのセロトニン] med./bio.

Magnetic field exposure during gestation: pineal and cerebral cortex serotonin in the rat.

掲載誌: Int J Dev Neurosci 2003; 21 (5): 263-266

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研究目的(著者による)

The effects of prenatal exposure to a 60 Hz magnetic field on the serotonin content in the cerebral cortex and pineal gland in young rats should be investigated.

詳細情報

Pregnant rats were divided into 3 groups (n=10 each): 1) exposure to the magnetic field, 2) sham exposure and 3) cage control. The offspring was killed and examined after 0, 15, 21 and 61 days after birth.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 60 Hz
ばく露時間: continuous for 5 min, twice/week (6 sessions in total) during gestation

ばく露1

主たる特性
周波数 60 Hz
タイプ
  • magnetic field
ばく露時間 continuous for 5 min, twice/week (6 sessions in total) during gestation
ばく露装置
ばく露の発生源/構造
チャンバの詳細 ventilated PVC tube (5 x 30 cm) inside a cylindrical exposure chamber (10 x 25 cm)
ばく露装置の詳細 25 cm long coil with three layers of wire 22 AWG (1059 total turns)
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
磁束密度 3.636 mT - - - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

A significant increase of the serotonin content was found in the cerebral cortex of exposed animals compared to the control group after 0, 15 and 21 days after birth. (Remark EMF-Portal: These are the results as they are described in the abstract and running text. The figures are partly contradictory and not clear. Moreover, a potential significance of the differences between the exposure and sham exposure group is not stated or shown clearly.)
All other parameters were not significantly different between the groups.
The authors conclude that prenatal exposure to a 60 Hz magnetic field might increase the serotonin content in the cerebral cortex of newborn rats.

研究の種別:

研究助成

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