研究のタイプ: 医学/生物学の研究 (experimental study)

[ラットの前頭葉でのドーパミン、セロトニンの分泌のターンオーバを極低周波磁界は増加させる] med./bio.

Alternating extremely low frequency magnetic field increases turnover of dopamine and serotonin in rat frontal cortex.

掲載誌: Bioelectromagnetics 2004; 25 (6): 426-430

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研究目的(著者による)

To investigate the effects of extremely low frequency magnetic fields on brain levels of some biogenic amines in rat.

詳細情報

The endogenous levels of the following biogenic amines and metabolites were determined: dopamine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, 3-methoxytyramine, 5-hydroxytryptamine, 5-hydroxyindoleacetic acid, and noradrenaline. Also the turnover of dopamine and 5-hydroxytryptamine was determined via an enzymatic test.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 10 Hz
ばく露時間: repeated daily exposure, 1 h/day for 14 days
  • 磁束密度: 1.8 mT effective value (to 3.8 mT maximum value)

ばく露1

主たる特性
周波数 10 Hz
タイプ
  • magnetic field
波形
  • sinusoidal
ばく露時間 repeated daily exposure, 1 h/day for 14 days
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 Animals were placed in a specially designed plastic chamber that was fitted inside the cylindrical applicator of the magnetic therapy device "Ambient 2000"
パラメータ
測定量 種別 Method Mass 備考
磁束密度 1.8 mT effective value 測定値 - to 3.8 mT maximum value

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

It was found that 1 h daily exposure for 2 weeks to extremely low frequency magnetic fields did not alter the endogenous levels of the examined amines and metabolites. However, the rate of synthesis (turnover) of dopamine and 5-hydroxytryptamine was increased.

研究の種別:

研究助成

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