研究のタイプ: 医学/生物学の研究 (experimental study)

[携帯電話ばく露後のラット脳での特異的mRNAレベルのアップレギュレーション] med./bio.

Upregulation of specific mRNA levels in rat brain after cell phone exposure.

掲載誌: Electromagn Biol Med 2008; 27 (2): 147-154

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研究目的(acc. to editor)

To check the hypothesis that cell phone irradiation can cause cellular damage to the rat brain leading to increased mRNA transcription of injury-associated proteins.

詳細情報

Fourteen 3-month-old male adult rats, weighing 250 to 350 g, were used.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 1.9 GHz
ばく露時間: repeated daily exposure, 2 x 3 h/day, for 18 weeks

ばく露1

主たる特性
周波数 1.9 GHz
タイプ
  • electromagnetic field
ばく露時間 repeated daily exposure, 2 x 3 h/day, for 18 weeks
Modulation
Modulation type unspecified
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
Distance between exposed object and exposure source 1 cm
チャンバの詳細 The rats were placed in holding units consisting of ventilated 5.1 cm x 15.2 cm PVC tubes fitted with 0.59-liter clear plastic bottle tops on one end and common 7.6-cm bolts with nuts at the other end. As the rats grew larger, new units were made using 8.9-cm PVC tubes, 1-liter bottles, and 10.2-cm bolts with nuts.
ばく露装置の詳細 Each cell phone was positioned 1 cm from the head of the rats, at equal distances between two rats in holding chambers.
Sham exposure A sham exposure was conducted.
Additional information Rats were exposed for 3 hours, followed by a 30-minute rest period outside of the tubes and a second exposure for 3 more hours per day.
パラメータ
測定量 種別 Method Mass 備考
SAR 1.8 W/kg - 測定値 - AMPS
SAR 0.9 W/kg - 測定値 - CELL
SAR 1.18 W/kg - 測定値 - PCS

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

A statistically significant mRNA up-regulation of all investigated injury-associated proteins in the brains of rats exposed to cell phone irradiation was found. The differences in temperature measured were not statistically sinificant.
The authors conclude that relative chronic exposure to cell phone microwave irradiation may result in cumulative injuries that could eventually lead to clinically significant neurological damage.

研究の種別:

研究助成

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