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To study whether exposure to a mobile phone-like signal alters the integrity of the human blood-brain barrier and the blood-cerebrospinal fluid barrier using peripheral markers (transthyretin and S100B protein).
The protein transthyretin served as marker of alterations of the blood-cerebrospinal fluid barrier. Serum S100B protein was used as a putative marker of blood-brain barrier dysfunction.
The aim of the present study was to investigate previous cross-sectional study results (see Soderqvist et al. 2009a and Soderqvist et al. 2009b) further under more controlled conditions. 41 volunteers were exposed for 30 minutes.
Modulation type: pulsed
ばく露時間: continuous for 30 min
|ばく露時間||continuous for 30 min|
|Pulse width||0.577 ms|
|Repetition frequency||217 Hz|
|Distance between exposed object and exposure source||8.5 cm|
|SAR||1 W/kg||average over mass||-||1 g||-|
The data showed no statistically significant increase in the serum levels of S100B protein, while for transthyretin a statistically significant increase was found in the final blood sample 60 minutes after the end of the exposure as compared to the prior sample taken immediately after exposure. The clinical significance of this finding, if any, is unknown. Further randomized studies with use of additional more brain specific markers are needed.