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To study the effect of chronic exposure to a low intensity GSM-like signal on health and survival of unrestrained female rats kept under identical conditions.
During 1997-2008 two long-term (experiments I and II) and two life-long (experiments III and IV) experiments were performed. In the first two experiments (1997-2000) 12 exposed and 12 sham exposed rats (each experiment) were observed until all surviving rats were sacrificed at 25 (770 days; experiment I) or 19 months of age (580 days; experiment II). In the course of two survival experiments (experiments III and IV: 2002-2005 and 2005-2008) 30 exposed and 30 sham exposed animals (each experiment) were followed up until their natural end or when they became moribund and had to be euthanized (maximal survival time was 36-37 months).
Modulation type: pulsed
ばく露時間: continuous (except times for feeding, cleaning, health inspection, etc.): 24 months (exp. I), 17 (exp. II), 36 (exp. III), and 37 (exp. IV) months
|ばく露時間||continuous (except times for feeding, cleaning, health inspection, etc.): 24 months (exp. I), 17 (exp. II), 36 (exp. III), and 37 (exp. IV) months|
|Pulse width||577 µs|
|Repetition frequency||217 Hz|
|チャンバの詳細||exposure chambers were placed in two adjacent rooms (no windows) of equal dimensions (RF exposure and sham exposure); no mobile communication possible within the rooms; 12 hours light (28-35 lux) per 24 hours; detailed description of an identical exposure set-up (identical parameters and intensity) in Bartsch H. et al. (2002)|
|ばく露装置の詳細||12 unrestrained animals per cage, located within exposure chamber or sham chamber|
|Sham exposure||A sham exposure was conducted.|
|Additional information||exposure began with 52 (I), 53 (II) , 70 (III) or 63 (IV) days of age depending on experiment group; animals sacrificed at 25 (I) and 19 (II) months of age; groups III and IV observed until natural end|
In experiment I no adverse health effects of chronic exposure were detectable, neither by macroscopic nor microscopic pathological examinations. Also in experiment II no apparent macroscopic pathological changes due to irradiation were found.
Median survival was significantly shortened under exposure in experiments III and IV by 9.06%, i.e by 72 days in experiment III and 77 days in experiment IV as compared to the sham exposed rats. Both groups of animals of experiment III showed reduced median survival times by 6.25% compared to the corresponding groups of experiment IV which may be due to the fact that animals of experiment III were born in October and animals of experiment IV in May indicating that the month of birth affects life span.
From the data of the last two experiments it has to be concluded that chronic exposure to a low intensity GSM-like signal may exert negative health effects and shorten survival if treatment is applied sufficiently long and the observational period covers the full life span of the animals concerned. The data show that survival of rats kept under controlled laboratory conditions varies within certain limits depending on the month of birth. To further prove these complex interactions and processes it is necessary to systematically continue the experiments.