この研究は、若い成獣のウィスターアルビノ雄および雌ラットの血液脳関門透過性に対するパルス変調の900MHzおよび 1800MHz電磁放射（20分間：抄録では非熱的レベルとの記載のみ）の影響を調べた。静脈内投与された色素エバンスブルーの全脳内含有率により血液脳関門透過性を評価した。その結果、雄ラットでは、対照群に比べ、ばく露群のエバンスブルー含有率が有意に高く、また900MHz群より1800MHz群の方が有意に高かった；雌ラットでは、対照群に比べて1800MHz群は有意差がなかったが、900MHz群は有意に高かった、と報告している。
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The effects of exposure of rats to electromagnetic fields of 900 MHz or 1800 MHz on the permeability of the blood brain barrier should be investigated.
A total of 27 male and 26 female rats were divided into the following groups: 1) exposure of male rats to a 900 MHz EMF (n=9), 2) exposure of female rats to a 900 MHz EMF (n=8), 3) exposure of male rats to a 1800 MHz EMF (n=9), 4) exposure of female rats to a 1800 MHz EMF (n=9), sham exposure of 5) male and 6) female rats (n=9 each, control groups).
| 周波数 | 900 MHz |
|---|---|
| タイプ |
|
| 波形 |
|
| 特性 |
|
| ばく露時間 | continuous for 20 minutes |
| Modulation type | pulsed |
|---|---|
| Repetition frequency | 217 Hz |
| Additional information |
duty cycle of 577 µs |
| ばく露の発生源／構造 | |
|---|---|
| Distance between exposed object and exposure source | 10 cm |
| チャンバの詳細 | an ideal laboratory with no noise |
| ばく露装置の詳細 | body temperatures were measured by rectal temperature measurement before and after the exposure: it was not affected by exposure |
| Sham exposure | A sham exposure was conducted. |
| 周波数 | 1,800 MHz |
|---|---|
| タイプ |
|
| 波形 |
|
| 特性 |
|
| ばく露時間 | continuous for 20 minutes |
| Modulation type | pulsed |
|---|---|
| Repetition frequency | 217 Hz |
| Additional information |
duty cycle of 577 µs |
| ばく露の発生源／構造 |
|
|---|---|
| Distance between exposed object and exposure source | 10 cm |
In male rats, exposure to the electromagnetic fields of 900 MHz (group 1) and 1800 MHz (group 3) led to a significantly increased permeability of the blood brain barrier compared to the control group (group 5).
In female rats, only exposure to the 900 MHz EMF (group 2) resulted in a significantly increased permeability of the blood brain barrier compared to the control group (group 6).
The authors conclude that exposure of rats to electromagnetic fields of 900 MHz or 1800 MHz might increase the permeability of the blood brain barrier with sex-specific differences.
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