研究のタイプ: 医学/生物学の研究 (experimental study)

[イン・ビトロでの血小板機能に対するスマートフォン通話への30分間ばく露の急性影響] med./bio.

Acute effects of 30 minutes of exposure to a smartphone call on in vitro platelet function.

掲載誌: Blood Transfus 2017; 15: 249-253

この研究は、市販のスマートフォン(900 MHz、通話モード)をばく露装置として用い、16人の健康なボランティアから採血された血液標本(それぞれクエン酸混和後に2分された)へのばく露の影響を調べた。2分された標本の1本は30分間ばく露(スマートフォンから1cmの距離で)、別の1本は無ばく露対照に割り当てた。ばく露後に血小板の数、血小板の大きさの平均(MPV)、血小板機能(血小板機能分析器による)を測定した。ばく露群では、コラーゲン-エプネフリンによる凝集反応時間の有意な延長、MPVの相当程度の上昇が見られたが、コラーゲン-アデノシン二リン酸による凝集反応および血小板の数は変わらなかった、と報告している。

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研究目的(著者による)

The effects of exposure of human blood samples to a 900 MHz electromagnetic field on platelet function and structure should be investigated.

詳細情報

16 healthy volunteers from laboratory staff gave 2 blood samples, respectively. One sample from each donor was exposed to the electromagnetic field (exposure group), the other sample was prevented from "close contact" (see "expo parameters" for details) to sources of radiofrequency electromagnetic fields (control group).

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
ばく露時間: continuous for 30 minutes
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ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 30 minutes
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
Distance between exposed object and exposure source 1 cm
チャンバの詳細 3.5 ml evacuated plastic tube containing buffered sodium citrate
ばく露装置の詳細 samples were placed in a plastic rack in 1 cm distant from the chassis of a commercial smartphone placed in a horizontal position; immediately after the samples had been positioned in the plastic rack, a call was placed on the smartphone and the communication was manually activated with 3G and Wi-Fi connections disabled (remark EMF-Portal: it is unclear which signal was actually used for exposure); during this period, the rack with samples and smartphone was gently inverted upside-down once every 5 min to prevent sedimentation of corpuscular blood elements
Additional information control samples were placed in another plastic rack for 90 min. and the rack was gently inverted upside-down once every 5 min. during 30 min. period (as for the samples of the exposure group); the untreated blood samples were carefully prevented from being in close contact (< 1 m) to mobile phones or other radiofrequency sources throughout the study period
パラメータ

No parameters are specified for this exposure.

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Exposure of human blood to the electromagnetic field induced a significant prolongation of collagen-epinephrine aggregation and a significant increase of mean platelet volume compared to the control group. Collagen-ADP aggregation and platelet count did not show significant differences between the groups.
The authors conclude that exposure of human blood samples to a 900 MHz electromagnetic field might disturb platelet function and alter platelet structure.

研究の種別:

研究助成

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