Studientyp:
Medizinische/biologische Studie
(experimentelle Studie)
In vitro developmental neurotoxicity following chronic exposure to 50 Hz extremely low frequency electromagnetic fields (ELF-EMF) in primary rat cortical cultures
med./bio.
[Entwicklungs-Neurotoxizität in vitro nach einer chronischen Exposition bei 50 Hz niederfrequenten elektromagnetischen Feldern in primären kortikalen Kulturen von Ratten]
Von:
de Groot MW, van Kleef RG, de Groot A, Westerink RH
Die Zellen wurden in die folgenden Gruppen eingeteilt: Exposition bei dem Magnetfeld mit 1) 1 µT, 2) 10 µT, 3) 100 µT, 4) 1000 µT und 5) Schein-Exposition. Alle Daten wurden aus mindestens 3 unabhängigen Versuchen gewonnen.
double copper wired solenoid coils fitted into an incubator; coils consisted of one continuous copper conductor; the system generated AC and DC vertical field components
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Assessment of the neurotoxic potential of exposure to 50Hz extremely low frequency electromagnetic fields (ELF-EMF) in naive and chemically stressed PC12 cells
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(2010):
Effects of Acute and Chronic Low Frequency Electromagnetic Field Exposure on PC12 Cells during Neuronal Differentiation
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(2008):
Extremely low-frequency electromagnetic fields promote in vitro neurogenesis via upregulation of Ca(v)1-channel activity
McCreary CR et al.
(2006):
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Zhang Y et al.
(2005):
Influence of pulsed electromagnetic field with different pulse duty cycles on neurite outgrowth in PC12 rat pheochromocytoma cells
Fan W et al.
(2004):
The influence of magnetic fields exposure on neurite outgrowth in PC12 rat pheochromocytoma cells
McFarlane EH et al.
(2000):
Changes in neurite outgrowth but not in cell division induced by low EMF exposure: influence of field strength and culture conditions on responses in rat PC12 pheochromocytoma cells
Morgado-Valle C et al.
(1998):
The role of voltage-gated Ca2+ channels in neurite growth of cultured chromaffin cells induced by extremely low frequency (ELF) magnetic field stimulation
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