To study the possible biological effects of 1800 MHz GSM-like radiofrequency exposure on liver oxidative DNA damage and lipid peroxidation levels in non-pregnant and pregnant rabbits, and in their newborns.
18 non-pregnant and 18 pregnant rabbits were divided into four groups which were composed of nine rabbits: 1) non-pregnant control, 2) non-pregnant exposed rabbits, 3) pregnant control, 4) pregnant exposed animals. Newborns of the pregnant rabbits were also divided into two groups: 5) nine newborns of group 3 and 6) nine newborns of group 4 (intrauterine exposure during gestational period of day 15-22).
|Exposure duration||continuous for 15 min/day on 7 days|
|Pulse width||0.576 ms|
|Duty cycle||12.5 %|
|Repetition frequency||217 Hz|
No significant differences were found in liver 8-hydroxy-2-deoxyguanosine levels of exposure groups (group 2 and 4) compared to the controls (group 1 and 3). However, in exposure groups malondialdehyde level and lipid peroxidation (ferrous ion oxidation) levels were increased compared to group 1. However, no significant difference was found in malondialdehyde level of group 4 (pregnant exposed) with respect to group 3 (pregnant control).
Remark EMF-Portal: Lipid peroxidation level of group 4 (pregnant, exposed) was not statistically significant different compared to group 1 (non-pregnant, control). Compared to group 3 (pregnant, control) the level of group 4 was statistically significant decreased.
No significant differences were found in liver tissue of 8-hydroxy-2-deoxyguanosine and malondialdehyde levels between the newborn groups (group 6 and group 5) while lipid peroxidation (ferrous ion oxidation) was significantly increased in group 6 with respect to group 5.
The authors conclude that whole body exposure to 1800 MHz GSM-like radiofrequency may lead to oxidative damage.