研究のタイプ: 医学/生物学の研究 (experimental study)

[低電力密度のマイクロ波放射によるウサギ水晶体上皮細胞での早期の変化] med./bio.

Low power density microwave radiation induced early changes in rabbit lens epithelial cells.

掲載誌: Chin Med J (Engl) 2001; 114 (12): 1290-1294

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研究目的(著者による)

To study whether low power density microwave irradiation can induce irreversible changes in rabbit eye lens epithelial cells and the mechanisms of these changes.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 2.45 GHz
ばく露時間: continuous for 3 h
ばく露2: 2.45 GHz
ばく露時間: continuous for 3 h

ばく露1

主たる特性
周波数 2.45 GHz
ばく露時間 continuous for 3 h
Modulation
Modulation type unspecified
ばく露装置
ばく露の発生源/構造
  • WKZ-2 microwave emission machine
Distance between exposed object and exposure source 0.43 m
ばく露装置の詳細 The rabbits were kept at a room temperature of 25°C. Their heads were fixed so that the distance between the exposed eye and the microwave generator was kept constant at 43 cm. One eye was exposed while the other eye served as control. The eye used for control was shielded by covering it with a copper grid cloth. The rabbits were conscious and their eyes were open during the whole experiment.
パラメータ
測定量 種別 Method Mass 備考
電力密度 50 W/m² unspecified 測定値 - -

ばく露2

主たる特性
周波数 2.45 GHz
ばく露時間 continuous for 3 h
Modulation
Modulation type unspecified
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
Distance between exposed object and exposure source 0.43 m
パラメータ
測定量 種別 Method Mass 備考
電力密度 100 W/m² unspecified 測定値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
  • 感覚器
  • eye
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Lots of the epithelial cells were in the initial phase of apoptosis in the 5 mW/cm² microwave irradiation group. A large number of cells became secondary necrotic cells, and severe damage could be revealed in the group exposed to 10 mW/cm² microwave irradiation.
Low power densities of microwave irradiation can induce irreversible damage to rabbit eye lens epithelial cells.

研究の種別:

研究助成

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