研究のタイプ: 医学/生物学の研究 (experimental study)

[60GHzミリ波ばく露による眼の急性傷害] med./bio.

Acute ocular injuries caused by 60-GHz millimeter-wave exposure.

掲載誌: Health Phys 2009; 97 (3): 212-218

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研究目的(著者による)

The authors have developed an acute ocular injury model and they used this model to examine the clinical course of millimeter wave-induced damages (examination until seven weeks after exposure). They also determined the experimental conditions leading to reproducible induction of ocular injuries caused by millimeter wave exposure.

詳細情報

40 rabbits were irradiated with 60 GHz millimeter waves using either a horn antenna or one of two lens antennas (6 and 9 mm diameter; phi6, phi9).

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 60 GHz
ばく露時間: continuous for 30 min
ばく露2: 60 GHz
ばく露時間: continuous for 6 min
ばく露3: 60 GHz
ばく露時間: continuous for 6 min

ばく露1

主たる特性
周波数 60 GHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 30 min
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 horn antenna with a diameter of 15.5 mm placed 10 mm from the corneal apex; rabbit fixed in a holder; eyelids kept open with surgical tape
パラメータ
測定量 種別 Method Mass 備考
電力密度 475 mW/cm² - - - -

ばく露2

主たる特性
周波数 60 GHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 6 min
ばく露装置
ばく露の発生源/構造
  • lens antenna
ばく露装置の詳細 antenna with a diameter of 6 mm and 150 mm focal point; rabbit fixed in a holder; eyelids kept open with surgical tape
パラメータ
測定量 種別 Method Mass 備考
電力密度 1.898 mW/cm² - - - -

ばく露3

主たる特性
周波数 60 GHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 6 min
ばく露装置
ばく露の発生源/構造
  • lens antenna
ばく露装置の詳細 antenna with a diameter of 9 mm and 250 mm focal point; rabbit fixed in a holder; eyelids kept open with surgical tape
パラメータ
測定量 種別 Method Mass 備考
電力密度 1.898 mW/cm² - - - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
  • 感覚器
  • eye
調査の時期:
  • ばく露前
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

The three antennas caused varying damages to the eyelids or eyeglobes. They all caused thermal burns to the eyelids that eventually affected the degree of intraocular injury. The most reproducible injuries without concurrent eyelid edema and corneal desiccation (that also can cause corneal epithelium damage) were achieved using the phi6 lens antenna: exposure for six minutes led to an elevation of the corneal surface temperature (reaching 54.2 +/- 0.9°C) plus corneal edema and epithelial cell loss. Furthermore, mitotic cells appeared in the pupillary area of the eye lens epithelium. Anterior uveitis also occurred resulting in acute miosis, an increase in flares (as marker for ocular inflammation), and iris vasodilation or vessel leakage.
These data indicate that the three types of millimeter wave antennas can cause thermal injuries of varying types and levels. The thermal effects induced by millimeter waves can apparently penetrate below the surface of the eye.

研究の種別:

研究助成

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