研究のタイプ: 医学/生物学の研究 (observational study)

[超低周波磁界(ELF-EMF)の職業ばく露と末梢血リンパ球のナチュラルキラー活性] med./bio.

Extremely low frequency-magnetic fields (ELF-EMF) occupational exposure and natural killer activity in peripheral blood lymphocytes.

掲載誌: Sci Total Environ 2009; 407 (3): 1218-1223

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研究目的(著者による)

To study the possible effects of occupational extremely low frequency magnetic field exposure on natural killer cell cytotoxic activity in peripheral blood cells of workers engaged in different occupational activities not involving any exposure to chemical/physical factors.

詳細情報

Individual extremely low frequency magnetic field exposure of all participants (22 men, 30 women) was measured during three consecutive work-shifts using personal dosimeters and environmental, non-occupational exposure was also monitored. Workers were classified as low exposed (26 subjects, TWA ≤ 0.2 µT) and higher exposed workers (26 subjects; TWA > 0.2 µT).

影響評価項目

ばく露

ばく露 パラメータ
ばく露1:
  • unspecified
ばく露時間: low exposure group: 15.2 +/- 8.4 years; medium exposure group: 10.4 +/- 7.4 years; high exposure group: 11.77 +/- 9.27 years

ばく露1

主たる特性
周波数
  • unspecified
タイプ
  • magnetic field
ばく露時間 low exposure group: 15.2 +/- 8.4 years; medium exposure group: 10.4 +/- 7.4 years; high exposure group: 11.77 +/- 9.27 years
ばく露装置
ばく露の発生源/構造
  • 詳細不明
Additional information exposure measurements: 8 h/day occupational exposure, 16 h/d environmental exposure - for 3 days
パラメータ
測定量 種別 Method Mass 備考
磁束密度 0.21 µT mean 計算値 - time weighted average

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中

研究の主なアウトカム(著者による)

In higher exposed workers, a trend to reduced natural killer cell activity was found compared to low exposed, but the difference was not significant. A significant reduction in natural killer cell activity was observed in a subgroup of highest exposed workers (12 subjects; TWA >1 µT) compared to the low exposed.
In conclusion, the data suggest that occupational exposure to extremely low frequency magnetic field, at least at TWA levels exceeding 1 µT may induce a reduction of natural killer cell activity in peripheral blood lymphocytes.

研究の種別:

研究助成

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