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To study the possible effects of occupational extremely low frequency magnetic field exposure on natural killer cell cytotoxic activity in peripheral blood cells of workers engaged in different occupational activities not involving any exposure to chemical/physical factors.
The study was performed to confirm previous results with a larger study group (see Gobba et al. 2009).
Individual extremely low frequency magnetic field exposure of all participants (121 workers; 65 men and 56 women) was measured during two consecutive work-shifts using personal dosimeters and environmental, non-occupational exposure was also monitored. Workers were classified as low exposed (62 subjects, TWA ≤ 0,2 µT), medium exposed (35 subjects; 0.21-0.99 µT) and higher exposed workers (24 subjects; TWA ≥ 1 µT).
ばく露時間: low exposure group: 12.9 +/- 7.3 years; medium exposure group: 10.0 +/- 6.6 years; high exposure group: 12.0 +/- 8.8 years
|ばく露時間||low exposure group: 12.9 +/- 7.3 years; medium exposure group: 10.0 +/- 6.6 years; high exposure group: 12.0 +/- 8.8 years|
|Additional information||exposure measurement: continuous for 8 h/day on 2 days occupational exposure and 16 h/d domestic exposure|
|磁束密度||0.2 µT||average over time||測定値および計算値||-||maximum value for the low exposure group|
|磁束密度||0.21 µT||average over time||測定値および計算値||-||minimum value for the medium exposure group|
|磁束密度||0.99 µT||average over time||測定値および計算値||-||maximum value for the medium exposure group|
|磁束密度||1 µT||average over time||測定値および計算値||-||minimum value for the higher exposure group|
In higher exposed workers (exceeding 1 µT) natural killer cell activity was significantly reduced compared to low exposure group. In the medium exposure group a decrease was also observed, but the difference was not significant.
In conclusion, the data suggest that occupational exposure to extremely low frequency magnetic fields, at least at TWA levels exceeding 1 µT, may induce a decrease in natural killer cell activity in peripheral blood lymphocytes.