研究のタイプ: 医学/生物学の研究 (experimental study)

[モルモットの肝臓、精巣および腎臓に対する低周波電磁界の影響に関する組織学的研究] med./bio.

Histological studies of the low frequency electromagnetic fields effect on liver, testes and kidney in guinea pigs.

掲載誌: World Appl Sci J 2007; 2 (5): 509-511

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研究目的(著者による)

To investigate the effects of exposure to extremely low frequency magnetic fields on the morphology of the liver, kidney and testes of guinea pigs.

詳細情報

The animals were divided into six groups and exposed or sham exposed for five days: 1.) sham exposure 2 hours daily, 2.) exposure 2 hours daily (0.013 µT, 5 Hz), 3.) exposure 2 hours daily (0.207 µT, 50 Hz), 4.) sham exposure 4 hours daily, 5.) exposure 4 hours daily (0.013 µT, 5 Hz) and 6.) exposure 4 hours daily (0.207 µT, 50 Hz).
Remark EMF-Portal: No information about number of animals given.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 5 Hz
ばく露時間: daily for 2 hours or 4 hours on 5 consecutive days
ばく露2: 50 Hz
ばく露時間: daily for 2 hours or 4 hours on 5 consecutive days

ばく露1

主たる特性
周波数 5 Hz
タイプ
  • magnetic field
ばく露時間 daily for 2 hours or 4 hours on 5 consecutive days
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 Solenoid consisted of 15 rings of armature winding with each ring consisting of 100 rounds of wire (i.e. a total of 1500 rounds of wire), a function generator was connected to the solenoid
パラメータ
測定量 種別 Method Mass 備考
磁束密度 0.013 µT - - - -

ばく露2

主たる特性
周波数 50 Hz
タイプ
  • magnetic field
ばく露時間 daily for 2 hours or 4 hours on 5 consecutive days
ばく露装置
ばく露の発生源/構造
パラメータ
測定量 種別 Method Mass 備考
磁束密度 0.207 µT - - - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

In the liver of guinea pigs from group 5 (4 h daily, 5 Hz, magnetic flux density of 0.013 µT), a vacuolation of the cytoplasm was observed.
In the kidney of animals from group 5 (4 h daily, 5 Hz, 0.013 µT) and group 6 (4 h daily, 50 Hz, 0.207 µT), the epithelial cells of the tubules were swollen. Additionally, cell necrosis which caused a decrease in the lumen of the renal tubules was observed in these groups.
In the testes of animals from group 2 (2 h daily, 5 Hz, 0.013 µT) and group 5 (4 h daily, 5 Hz, 0.013 µT), atrophied seminiferous tubules and interstitial tissue was found as well as a decrease of leydig cells.
The authors conclude that extremely low frequency magnetic fields could affect the morphology of the liver, kidney and testes of guinea pigs.

研究の種別:

研究助成

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