Study type: Medical/biological study (experimental study)

Effect of exposure and withdrawal of 900-MHz-electromagnetic waves on brain, kidney and liver oxidative stress and some biochemical parameters in male rats. med./bio.

Published in: Electromagn Biol Med 2015; 34 (4): 279-284

Aim of study (acc. to author)

The effects of exposure of rats to a 900 MHz electromagnetic field on oxidative stress in the brain, liver and kidneys and some blood parameters should be investigated.

Background/further details

Rats were divided into four groups (n=10 each): 1) exposure: exposure to the electromagnetic field, 2) regeneration: exposure to the electromagnetic field and further housing for 30 days without exposure and 3) control group: no exposure.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: CW
Exposure duration: continuous for 1 hour/day for 60 days

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 1 hour/day for 60 days
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber aluminum cage of 100 x 50 x 50 cm; the mesh of the upper lid allowed entrance of the oscillator's antenna and good ventilation during the exposure period
Setup 5 rats were placed in each cage; an oscillator with a dipole antenna emitted waves regularly in all directions with same strength
Parameters
Measurand Value Type Method Mass Remarks
power 5 W peak value - - -
power density 2.5 mW/cm² mean - - -

Reference articles

  • El Nabarawy NA et al. (2011): Protective Effect of Caffeic Acid Phenethyl Ester (CAPE) on Liver and Kidney of Rats After Exposure to 900 MHz Electromagnetic Field.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In the serum of exposed rats (group 1), the levels of corticosterone, creatinine and urea as well as the enzyme activities of alanine transaminase and aspartate aminotransferase were significantly increased compared to the regeneration group (group 2) and control group (group 3).
The amount of malondialdehyde was significantly increased and the total antioxidant capacity was significantly decreased in brain, liver and kidneys of exposed rats compared to the regeneration group and control group.
There were no significant differences observed between the regeneration group and the control group.
The authors conclude that exposure of rats to a 900 MHz electromagnetic field could induce oxidative stress in the brain, liver and kidneys and change some blood parameters. The changed parameters might normalize during a subsequent regeneration phase without exposure.

Study character:

Study funded by

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