Study type: Medical/biological study (experimental study)

Effects of chronic exposure to 950 MHz ultra-high-frequency electromagnetic radiation on reactive oxygen species metabolism in the right and left cerebral cortex of young rats of different ages. med./bio.

Published in: Int J Radiat Biol 2015; 91 (11): 891-897

Aim of study (acc. to author)

The effects of a prenatal and postnatal exposure of rats to a 950 MHz electromagnetic field on oxidative damages of DNA, proteins and lipids in the cortex should be investigated.

Background/further details

Pregnant rats were divided into two groups (exposure and sham exposure, n=6 each) and were (sham) exposed from the first day of pregnancy until up to 6 days after birth of the pups. Directly after birth and 6 days thereafter, 6 pups from exposed dams and 6 pups from sham exposed dams were killed and investigated, respectively.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 950 MHz
Exposure duration: continuous for 30 min/day from the first day of gestation until birth
Exposure 2: 950 MHz
Exposure duration: continuous for 30 min/day from the first day of gestation until 6 days after birth

General information

further exposure reference: Sadiku, 2010: Elements of electromagnetics. 5th edition. London, UK: Oxford University Press.

Exposure 1

Main characteristics
Frequency 950 MHz
Type
Exposure duration continuous for 30 min/day from the first day of gestation until birth
Additional info vertical polarization
Exposure setup
Exposure source
Chamber polypropylene boxes (40.5 x 33.3 x 17.5 cm)
Setup boxes were placed 11 cm away from the antenna; exposure system was kept in an aluminium Faraday cage (101.5 x 64.0 x 38.0 cm; 0.5 cm mesh); cages were placed on a wooden tray
Sham exposure A sham exposure was conducted.
Additional info the cage with the sham-exposed group was placed 92 cm away from the cage of the exposure group
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 35 V/m spatial average measured - -
electric field strength 52.1 V/m maximum measured - -
electric field strength 13.5 V/m minimum measured - -
power 1 W - - - -
SAR 1.32 W/kg - calculated - for pups on day of birth
electric field strength 32.8 V/m - calculated - internal electric field in the brain of newborn rats
SAR 0.44 W/kg - calculated - for dams on first day of gestation

Exposure 2

Main characteristics
Frequency 950 MHz
Type
Exposure duration continuous for 30 min/day from the first day of gestation until 6 days after birth
Additional info vertical polarization
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 35 V/m spatial average measured - -
electric field strength 52.1 V/m maximum measured - -
electric field strength 13.5 V/m minimum measured - -
power 1 W - - - -
SAR 1.14 W/kg - calculated - for pups on day 6 of birth
SAR 0.35 W/kg - calculated - for dams on day 6 after birth
electric field strength 33.8 V/m - calculated - internal electric field in brain of 6 day old pups

Reference articles

  • Furtado-Filho OV et al. (2014): Effect of 950 MHz UHF Electromagnetic radiation on biomarkers of oxidative damage, metabolism of UFA and antioxidants in the liver of young rats of different ages.
  • Peyman A et al. (2001): Changes in the dielectric properties of rat tissue as a function of age at microwave frequencies.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Newborn rats from exposed dams had a significantly reduced body weight in comparison to rats from sham exposed dams.
6-day-old exposed rats showed a significantly higher amount of carbonyl proteins in the right cortex and a significantly lower blood glucose level compared to the sham exposure group.
All other parameters did not show any significant differences between the exposure groups and the respective sham exposure groups.
The authors conclude that a prenatal and postnatal exposure of rats to a 950 MHz electromagnetic field does not seem to induce oxidative damages of DNA, proteins and lipids in the cortex.

Study character:

Study funded by

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