研究のタイプ: 医学/生物学の研究 (experimental study)

[ヒト白血球の熱ショックタンパク質の非熱的誘導に対する900 MHz電磁界の影響] med./bio.

Effect of 900 MHz electromagnetic fields on nonthermal induction of heat-shock proteins in human leukocytes.

掲載誌: Radiat Res 2005; 163 (1): 45-52

The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →

研究目的(著者による)

To study whether exposure to mobile phone-type irradiation causes a nonthermal stress response in human leukocytes.

詳細情報

Positive (heat-stressed at 42°C) and negative (kept at 37°C) control samples were incubated simultaneously.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: CW
ばく露時間: continuous for 4 hours
This study was performed to investigate the effects of different power levels.
  • SAR: 0.4 W/kg mean (unspecified) (input power level of 3 W)
  • SAR: 2 W/kg mean (unspecified) (input power level of 14 W)
  • SAR: 3.6 W/kg mean (unspecified) (input power level of 25 W)
ばく露2: 900 MHz
Modulation type: CW
ばく露時間: continuous for 20 min, 1 h or 4 h
This study was performed to investigate the effects of different exposure durations.
  • SAR: 2 W/kg mean (unspecified)
ばく露3: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 20 min, 1 h or 4 h
This study was performed to investigate the effects of different exposure durations using a GSM signal.
  • SAR: 0.4 W/kg mean (unspecified)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 4 hours
Additional information This study was performed to investigate the effects of different power levels.
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 The human peripheral blood was exposed or sham-exposed in Petri dishes in a calibrated TEM cell placed in an incubator. The cell was operated in travelling wave mode, being terminated by a matched load, which increased the uniformity of the exposure.
Additional information Positive (heat-stressed at 42°C) and negative (kept at 37°C) control groups were incubated simultaneously in the same incubator. The sham-exposed dish and the positive control were heated by heater mats, the negative control was in equilibrium with the incubator temperature. The peak static magnetic flux density generated by the heater mat and measured 2 mm above the mat using an incremental gaussmeter was below 15 µT.
パラメータ
測定量 種別 Method Mass 備考
SAR 0.4 W/kg mean 測定値および計算値 unspecified input power level of 3 W
SAR 2 W/kg mean 測定値および計算値 unspecified input power level of 14 W
SAR 3.6 W/kg mean 測定値および計算値 unspecified input power level of 25 W

ばく露2

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 20 min, 1 h or 4 h
Additional information This study was performed to investigate the effects of different exposure durations.
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
SAR 2 W/kg mean 計算値 unspecified -

ばく露3

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 20 min, 1 h or 4 h
Additional information This study was performed to investigate the effects of different exposure durations using a GSM signal.
Modulation
Modulation type pulsed
Duty cycle 12.5 %
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
SAR 0.4 W/kg mean 計算値 unspecified -

Reference articles

  • Lim HB et al. (2002): [携帯電話からの近傍界がヒト全血のストレス反応メカニズムに与える影響を定量化するためのRFドシメトリ装置のFDTD構造]

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Heat caused an increase in the number of cells expressing stress proteins (HSP70, HSP27) and this increase was dependent on time. However, no statistically significant difference was detected in the number of cells expressing stress proteins after exposure. These data suggest that mobile phone-type irradiation is not a stressor of normal human lymphocytes and monocytes, in contrast to mild heating.

研究の種別:

研究助成

関連論文