この研究は、雌ラットを、2つの2100MHz無線周波放射（RFR）ばく露群とそれぞれの擬似ばく露対照群に分け、2つのばく露群は、6時間／日、週5日のばく露をそれぞれ、2週間（ばく露日数10日）または8週間（同40日）与えた。ばく露終了後に、脳のゲノム含有DNAを抽出し、酸化的DNA損傷およびマロンジアルデヒド（MDA）を分析した。その結果、脳の酸化的DNA損傷は、それぞれの対照群に比べ10日ばく露群では増加、40日ばく露群では減少した；40日ばく露群ではMDAの減少も観察された、と報告している。
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The effects of exposure of rats to a 2100 MHz electromagnetic field on oxidative stress and DNA damage in the brain should be investigated.
Female rats were divided into the following groups: 1) exposure to the electromagnetic field for 2 weeks (n=9), 2) sham exposure for 2 weeks (n=6), 3) exposure to the electromagnetic field for 8 weeks (n=9), 4) sham exposure for 8 weeks (n=6). Two days after the last respective (sham) exposure, the rats were anesthetized, killed and examined.
| 周波数 | 2,100 MHz |
|---|---|
| タイプ |
|
| 特性 |
|
| Modulation type | cf. additional information |
|---|
| ばく露の発生源／構造 | |
|---|---|
| Distance between exposed object and exposure source | 12 cm |
| Sham exposure | A sham exposure was conducted. |
The amount of oxidative DNA damage was significantly increased after two weeks of exposure (group 1) compared to the control group (group 2), whereas no differences were found in lipid peroxidation.
After 8 weeks of exposure (group 3), oxidative DNA damage as well as lipid peroxidation were significantly reduced compared to the control group (group 4).
The authors conclude that an acute exposure of rats to a 2100 MHz electromagnetic field could cause oxidative DNA damage in the brain. However, chronic exposure could also lead to the adaptation and stimulation of DNA repair mechanisms.
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