研究のタイプ: 医学/生物学の研究 (experimental study)

Influence of alternating magnetic fields on two-dimensional tumor growth. med./bio.

掲載誌: Electro Magnetobiol 2000; 19 (3): 351-355

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研究目的(著者による)

The effects of exposure to extremely low frequency magnetic fields on in vitro glioblastoma tumor growth should be investigated.

詳細情報

C6 rat glioblastoma cells were plated in Petri dishes and divided into the following groups (5 dishes per group): 1) exposure to 10 Hz magnetic field, 2) exposure to 20 Hz magnetic field, 3) exposure to 30 Hz magnetic field, 4) exposure to 40 Hz magnetic field, 5) exposure to 50 Hz magnetic field, 6) control group. Dishes were examined every 10 hours during exposure.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 10 Hz
ばく露時間: 70 hours
ばく露2: 20 Hz
ばく露時間: 70 hours
ばく露3: 30 Hz
ばく露時間: 70 hours
ばく露4: 40 Hz
ばく露時間: 70 hours
ばく露5: 50 Hz
ばく露時間: 70 hours

ばく露1

主たる特性
周波数 10 Hz
タイプ
  • magnetic field
ばく露時間 70 hours
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 a pair of horizontal rectangular coils (25 x 15 cm) was placed in a pseudo-Helmholtz configuration (distance between the coils was 15 cm); Petri dishes were placed between the coils; the magnetic field was uniform within 7% in the center of the coils; the whole system was placed in a temperature-controlled box kept at 37.0 ± 0.1°C
パラメータ
測定量 種別 Method Mass 備考
磁束密度 10 mT - 測定値 - -

ばく露2

主たる特性
周波数 20 Hz
タイプ
  • magnetic field
ばく露時間 70 hours
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
磁束密度 10 mT - 測定値 - -

ばく露3

主たる特性
周波数 30 Hz
タイプ
  • magnetic field
ばく露時間 70 hours
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
磁束密度 10 mT - 測定値 - -

ばく露4

主たる特性
周波数 40 Hz
タイプ
  • magnetic field
ばく露時間 70 hours
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
磁束密度 10 mT - 測定値 - -

ばく露5

主たる特性
周波数 50 Hz
タイプ
  • magnetic field
ばく露時間 70 hours
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
磁束密度 10 mT - 測定値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露前
  • ばく露中

研究の主なアウトカム(著者による)

Tumor growth was increased at each frequency of the magnetic field (groups 1-5) compared to the control group. The highest growth rate was observed at 20 Hz (group 2).
(Remark EMF-Portal: There was no data on statistical significance of these results.)
The authors conclude that exposure to extremely low frequency magnetic fields might accelerate the in vitro glioblastoma tumor growth.

研究の種別:

研究助成

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