Study type: Medical/biological study (experimental study)

Endometrial Apoptosis Induced by a 900-MHz Mobile Phone: Preventive Effects of Vitamins E and C. med./bio.

Published in: Adv Ther 2006; 23 (6): 957-973

Aim of study (acc. to author)

To study the effects of an electromagnetic field emitted by a mobile phone on endometrial apoptosis and lipid peroxidation in the rat and to study the ameliorating effects of a combination of vitamin E and vitamin C against electromagnetic field damage.

Background/further details

24 rats were divided in three groups: (1) sham-exposed group, (2) electromagnetic field exposed group, and (3) electromagnetic field exposed group, treated with vitamin E and vitamin C (administered before daily exposure).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 30 min/day, for 30 days
  • power: 2 W peak value
  • power density: 1.04 mW/cm²
  • SAR: 4 W/kg maximum (whole body)
  • SAR: 0.016 W/kg minimum (whole body)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration repeated daily exposure, 30 min/day, for 30 days
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
Exposure setup
Exposure source
Setup A special device with antennae for insulated exposure was used. The individual animal was placed in a ventilated plastic tube cage (5 cm in diameter, 12 cm long) positioned over a half-wave dipole antenna.
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power 2 W peak value measured - -
power density 1.04 mW/cm² - measured - -
SAR 4 W/kg maximum measured whole body -
SAR 0.016 W/kg minimum measured whole body -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Exposure to 900 MHz electromagnetic field emitted by a mobile phone may cause endometrial apoptosis and oxidative stress: partly significantly differences in immunohistochemistry of caspase-3, caspase-8, Bcl-2 and Bax between exposed groups and control group were found as well as increased malondialdehyde level in exposed groups. However, treatment with vitamin E and vitamin C could diminish these changes and may have a beneficial effect in preventing endometrial changes in rats.

Study character:

Study funded by

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