研究のタイプ: 医学/生物学の研究 (experimental study)

[900 MHz携帯電話によるアポト-シス:ビタミンEとCの予防効果] med./bio.

Endometrial Apoptosis Induced by a 900-MHz Mobile Phone: Preventive Effects of Vitamins E and C.

掲載誌: Adv Ther 2006; 23 (6): 957-973

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研究目的(著者による)

To study the effects of an electromagnetic field emitted by a mobile phone on endometrial apoptosis and lipid peroxidation in the rat and to study the ameliorating effects of a combination of vitamin E and vitamin C against electromagnetic field damage.

詳細情報

24 rats were divided in three groups: (1) sham-exposed group, (2) electromagnetic field exposed group, and (3) electromagnetic field exposed group, treated with vitamin E and vitamin C (administered before daily exposure).

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: repeated daily exposure, 30 min/day, for 30 days

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 repeated daily exposure, 30 min/day, for 30 days
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 A special device with antennae for insulated exposure was used. The individual animal was placed in a ventilated plastic tube cage (5 cm in diameter, 12 cm long) positioned over a half-wave dipole antenna.
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
電力 2 W peak 測定値 - -
電力密度 1.04 mW/cm² - 測定値 - -
SAR 4 W/kg maximum 測定値 whole body -
SAR 0.016 W/kg minimum 測定値 whole body -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Exposure to 900 MHz electromagnetic field emitted by a mobile phone may cause endometrial apoptosis and oxidative stress: partly significantly differences in immunohistochemistry of caspase-3, caspase-8, Bcl-2 and Bax between exposed groups and control group were found as well as increased malondialdehyde level in exposed groups. However, treatment with vitamin E and vitamin C could diminish these changes and may have a beneficial effect in preventing endometrial changes in rats.

研究の種別:

研究助成

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