研究のタイプ: 医学/生物学の研究 (experimental study)

[ラットの新陳代謝に対する低周波・低強度電磁界の影響] med./bio.

Effects of electromagnetic fields of low frequency and low intensity on rat metabolism.

掲載誌: Biomagn Res Technol 2008; 6: 3

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研究目的(著者による)

This study should investigate whether the exposure to low frequency athermal electromagnetic fields exerts influence on basic metabolic processes in rats.

詳細情報

Altogether 16 male rats, eight adult animals in the age of 8-12 weeks, and eight aging animals in the age of 68-72 weeks were used. After the first blood drawing three rats died. Blood samples were collected first after a 15 days adaption period, second after first half of irradiation (after fourteen days), third after second half of irradiation, fourth after one week period without irradiation, and fifth after a second irradiation of fourteen days. The body weight was measured at the same time points. Exposure results were compared to normal physiological parameter values for this rat strain.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 31.6 Hz
ばく露時間: continuous for 50 days
ばく露2: 31.6 Hz
ばく露時間: continuous for 50 days

ばく露1

主たる特性
周波数 31.6 Hz
タイプ
  • magnetic field
ばく露時間 continuous for 50 days
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 diameter of the coil: 75 cm; rats placed in the middle of the coil
パラメータ
測定量 種別 Method Mass 備考
磁束密度 40 µT - 測定値 - -

ばく露2

主たる特性
周波数 31.6 Hz
タイプ
  • magnetic field
ばく露時間 continuous for 50 days
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 stack of 5 Helmholtz coils
パラメータ
測定量 種別 Method Mass 備考
磁束密度 35.5 µT minimum 測定値 - -
磁束密度 51.6 µT maximum 測定値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
  • lung, heart, spleen, liver, pancreas, kidney, skeletal muscle, brain, eye
調査の時期:
  • ばく露前
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

After seven weeks of exposure rats showed an increase in body weight compared to historical data. The blood glucose increased more in aging than in adult animals at the end of exposure. The circulating levels of specific free fatty acids revealed clear difference between the initial values and the final ones. A frequent finding of histopathological examination was hepatic glycogenosis.
In conclusion, these data give evidence that the long term exposure electromagnetic fields with a well defined frequency may have relevant effects on parameters such as body weight, blood glucose and fatty acid metabolism.

研究の種別:

研究助成

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