研究のタイプ: 医学/生物学の研究 (experimental study)

[ラットの血液脳関門透過性および神経変性に対する頭部限定のGSM-900ばく露の影響] med./bio.

Effects of head-only exposure of rats to GSM-900 on blood-brain barrier permeability and neuronal degeneration.

掲載誌: Radiat Res 2009; 172 (3): 359-367

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研究目的(acc. to editor)

The aim of this study was to perform a confirmation study of Salford et al. 2003 using well-controlled conditions (age and sex of animals, animal facility, restrainer habituation, exposure conditions) and thus to study the effects of radiofrequency exposure on the permeability of blood-brain barrier and on neuron degeneration.

詳細情報

Five groups of 16 rats were exposed to SAR values of 0, 0.14 and 2.0 W/kg. Cage control (n=8) and positive controls (subjected to cold shock to induce brain damage; n=10) were also performed.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
ばく露時間: continuous for 2 hr
  • SAR: 0.14 W/kg average over mass (brain)
  • SAR: 2 W/kg average over mass (brain)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 2 hr
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 during exposure rats kept in a cylinder with a cone of Plexiglas
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 0.14 W/kg average over mass - brain -
SAR 2 W/kg average over mass - brain -

Reference articles

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Exposure of rat brains at two SAR values induced no neuronal degeneration, permeability of blood-brain barrier or neuronal apoptosis. These data differ from those obtained by Salford et al. 2003 even at the higher SAR of 2 W/kg, i.e. ten times higher than the maximum used by the Swedish group.
The authors conclude that, under these exposure conditions, GSM-900 radiofrequency irradiation does not generate brain damage at levels up to the standard local exposure limit for the public.

研究の種別:

研究助成

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