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30 three-month old rats were divided into 3 groups (n=10 each): 1) exposure for 8 weeks (three weeks intrauterine and five weeks ectopic (?)), 2) exposure for 13 weeks (three weeks intrauterine and ten weeks ectopic (?)), 3) non-exposed control group.
(remark EMF-Portal: The exposure conditions and the experimental design are not clear. The three-month old rats were probably pregnant and their offspring was exposed and investigated.)
ばく露時間: for 8 weeks (3 weeks intrauterine + 5 weeks ectopic)
ばく露時間: for 13 weeks (3 weeks intrauterine + 10 weeks ectopic)
In the control group (group 3), the thickness of the zona pellucida and the Theca layer were regular.
In group 1 (8 week exposure), the thickness of the zona pellucida and the Theca layer were irregular in some parts.
In group 2 (13 week exposure), disappearance and destruction of granulosa of the growing primary follicles and irregular oocytes in the follicle were observed. Additionally, the structure of the ovarian stroma was disrupted and accumulation of collagen fibers in the form of fibrosis was observed in parts of the stroma.
The atresia (i.e. breakdown) of the ovarian follicles was significantly different (not further specified) in both exposure groups compared to the control group.
The authors conclude that exposure of rats to a 50 Hz or 60 Hz magnetic field might affect the histology of ovarian follicles.