研究のタイプ: 医学/生物学の研究 (experimental study)

[ヒト精子に対する1950 MHzのW-CDMA様信号の影響] med./bio.

Effects of 1950 MHz W-CDMA-like signal on human spermatozoa.

掲載誌: Bioelectromagnetics 2016; 37 (6): 373-381

この研究は、温度制御下での1950 MHzのW-CDMA様電磁信号(SARは2.0または6.0W/kg)の1時間ばく露がヒト精子に与える影響(精子の運動および動力学的変数)について、コンピュータ支援精子分析装置を用いて調べた。また、DNA損傷を評価するため、8-ハイドロキシ-2'-デオキシグアノシン(8-OHdG)陽性を示した精子の割合をフローサイトメトリで測定した。その結果、精子運動性、動力学的変数、8-OHdG陽性レベルのいずれにおいても、ばく露群と擬似ばく露群の間に有意差は観察されなかった;これまでの何件かの研究報告と今回の研究結果との不一致は、さまざまなばく露状況、湿度、温度制御、ベースラインの精子特性、精子提供者の年齢によって説明できるかも知れない、と報告している。

The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →

研究目的(著者による)

The effects of exposure of human sperms to a 1950 MHz electromagnetic field (W-CDMA) on sperm motility and oxidative stress should be investigated.

詳細情報

Good-quality sperms from semen samples from 50 healthy subjects were isolated and 2 specimens were created from each sample for exposure and sham exposure, respectively (remark EMF-Portal: the real number of specimens in each group is unclear as there were 2 exposure groups (SAR of 2 W/kg and 6 W/kg) and two respective sham exposure groups).
Positive control for oxidative stress was performed.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 1,950 MHz
ばく露時間: continuous for 1 hour
  • SAR: 2 W/kg mean
ばく露2: 1,950 MHz
ばく露時間: continuous for 1 hour
  • SAR: 6 W/kg mean

ばく露1

主たる特性
周波数 1,950 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 1 hour
Additional information W-CDMA-like signal
ばく露装置
ばく露の発生源/構造
チャンバの詳細 petri dishes in exposure system inside incubator
ばく露装置の詳細 exposure system consisted of two waveguides (one for exposure, the other one for sham exposure); it was placed in the incubator under controlled conditions at 37°C with high humidity; each waveguide contained one or two specimens at a time; temperature difference between the two waveguides during exposure was kept to less than 0.1°C
Sham exposure A sham exposure was conducted.
Additional information waveguides that were used for the real or sham exposure were randomized by a computer
パラメータ
測定量 種別 Method Mass 備考
SAR 2 W/kg mean - - -

ばく露2

主たる特性
周波数 1,950 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 1 hour
Additional information W-CDMA-like signal
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 6 W/kg mean - - -

Reference articles

  • Gong Y et al. (2014): [1950 MHzでの受精能研究のための2層細胞培養構造に関するドシメトリ評価]

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

No significant differences were found between the exposure groups and respective sham exposure groups in any parameter.
The authors conclude that there is no evidence for any effect of exposure of human sperms to a 1950 MHz electromagnetic field (W-CDMA) on sperm motility and oxidative stress.

研究の種別:

研究助成

関連論文