研究のタイプ: 医学/生物学の研究 (experimental study)

[900MHz電磁界ばく露後の成獣雌ラット小脳におけるプルキンエ細胞数の減少] med./bio.

Purkinje cell number decreases in the adult female rat cerebellum following exposure to 900 MHz electromagnetic field.

掲載誌: Brain Res 2010; 1356: 95-101

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研究目的(著者による)

To study the effect of electromagnetic field exposure on the Purkinje cell number in the cerebellum of adult female rats.

詳細情報

Animals were divided into three groups: control group (n=5), sham exposure group (n=6), and exposure group (n=6).

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
ばく露時間: continuous for 1h/day for 28 days

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 1h/day for 28 days
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 rats placed in round plastic tube cages perpendicular to the antenna with a distance of 1 cm between them, the heads positioned in the direction of the antenna; positions of the rats changed daily
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 0.016 W/kg - - whole body -
SAR 2 W/kg - - brain -
電力 2 W peak - - -
電力密度 1 mW/cm² - 測定値 - +/- 0.4 mW/cm²

Reference articles

  • Bas O et al. (2009): [900MHz電磁界ばく露は成獣雌ラットの海馬錐体細胞の定性的および定量的特徴に影響を与える]
  • Bas O et al. (2009): [900 MHz電磁界への出生前の慢性ばく露は新生仔ラットの海馬の錐体細胞消失を生じる]
  • Odaci E et al. (2008): [ラット歯状回に対する900 MHz電磁界の出生前ばく露の影響:立体学的および組織病理学的研究]
  • Yildiz M et al. (2006): [ラットの骨ミネラル密度に対する電磁界の影響並びにCAPEの防護効果]
  • Koylu H et al. (2006): [メラトニンはラット脳における900 MHzマイクロ波誘導過酸化脂質変化を変調させる]
  • Koyu A et al. (2005): [ラットのTSHおよび甲状腺ホルモンに対する900 MHz電磁界の影響]

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The data showed that the total number of Purkinje cells in the cerebellum of the exposed rats was significantly lower than those of the control group and sham exposure group. There was no significant difference between the rats' body and brain weights in the three groups.
The authors suggest that long-term exposure to 900 MHz electromagnetic fields leads to decreases of Purkinje cell numbers in the female rat cerebellum.

研究の種別:

研究助成

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