研究のタイプ: 医学/生物学の研究 (experimental study)

[900MHz電磁界ばく露は成獣雌ラットの海馬錐体細胞の定性的および定量的特徴に影響を与える] med./bio.

900 MHz electromagnetic field exposure affects qualitative and quantitative features of hippocampal pyramidal cells in the adult female rat.

掲載誌: Brain Res 2009; 1265: 178-185

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研究目的(著者による)

To investigate the effect of postnatal exposure to a 900 MHz electromagnetic field on the number of pyramidal cells in the Cornu Ammonis of the hippocampus in rats.

詳細情報

Female rats (12 weeks old) were assigned to a cage control (n=6), an exposure group (n=6) and a sham exposure group (n=6). All rats were sacrificed at the end of 16 weeks.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: CW
ばく露時間: 1 h/day for 28 days

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 1 h/day for 28 days
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
Distance between exposed object and exposure source 1 cm
ばく露装置の詳細 antenna placed inside the tube cage
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 0.016 W/kg - - whole body -
SAR 2 W/kg average over mass - brain -
電力 2 W peak - - -
電力密度 1 mW/cm² - 測定値 - -

Reference articles

  • Odaci E et al. (2008): [ラット歯状回に対する900 MHz電磁界の出生前ばく露の影響:立体学的および組織病理学的研究]
  • Yildiz M et al. (2006): [ラットの骨ミネラル密度に対する電磁界の影響並びにCAPEの防護効果]
  • Koylu H et al. (2006): [メラトニンはラット脳における900 MHzマイクロ波誘導過酸化脂質変化を変調させる]
  • Koyu A et al. (2005): [ラットのTSHおよび甲状腺ホルモンに対する900 MHz電磁界の影響]

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

There was no significant difference in body weight between the exposure group compared to the cage control and the sham exposure group.
Dark cell density (=damaged cells) was significantly increased in the exposure group compared to the cage control and the sham exposure group. Postnatal exposure caused a significant decrease of the pyramidal cell number in the Cornu Ammonis of the exposure group.
Chronic exposure of 900 MHz electromagnetic fields may play a critical role in the neuronal development of the hippocampus.

研究の種別:

研究助成

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