Medizinische/biologische Studie (experimentelle Studie)

Investigation of the effects of 2.1 GHz microwave radiation on mitochondrial membrane potential (DeltaPsim), apoptotic activity and cell viability in human breast fibroblast cells med./bio.

[Untersuchung der Wirkungen von 2,1 GHz-Mikrowellen-Feldern auf das Mitochondrien-Membran-Potential (Delta Psi), Apoptose-Aktivität und Zelllebensfähigkeit bei menschlichen Brust-Fibroblasten-Zellen]

Von: Esmekaya MA, Seyhan N, Kayhan H, Tuysuz MZ, Kursun AC, Yagci M

Veröffentlicht in: Cell Biochem Biophys 2013; 67 (3): 1371-1378

Exposition	Parameter
Exposition 1: 2,1 GHz Expositionsdauer: kontinuierlich für 4 oder 24 Stunden	Leistungsflussdichte: 0,142 mW/cm² SAR: 0,607 W/kg räumlicher Mittelwert (10 g) Leistung: 1 W (Eingangs-Leistung)

Frequenz	2,1 GHz
Typ	elektromagnetisches Feld
Expositionsdauer	kontinuierlich für 4 oder 24 Stunden

Expositionsquelle	Hornantenne
Kammer	cells were grown in 24-well culture plates in humidified cell incubator at 37°C under 5 % CO₂ and 95 % air
Aufbau	24 well-plate was placed above the transmitting antenna
Schein-Exposition	Eine Schein-Exposition wurde durchgeführt.

Messgröße	Wert	Typ	Methode	Masse	Bemerkungen
Leistungsflussdichte	0,142 mW/cm²	-	-	-	-
SAR	0,607 W/kg	räumlicher Mittelwert	berechnet	10 g	-
Leistung	1 W	-	-	-	Eingangs-Leistung

Zeni O et al. (2012): Radiofrequency radiation at 1950 MHz (UMTS) does not affect key cellular endpoints in neuron-like PC12 cells

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Studienmerkmale:

Esmekaya MA et al. (2017): Mitochondrial hyperpolarization and cytochrome-c release in microwave-exposed MCF-7 cells
Lee SS et al. (2014): Influence of smartphone Wi-Fi signals on adipose-derived stem cells
Sekijima M et al. (2010): 2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells
Joubert V et al. (2008): Apoptosis is Induced by Radiofrequency Fields through the Caspase-Independent Mitochondrial Pathway in Cortical Neurons
Hoyto A et al. (2008): Proliferation, Oxidative Stress and Cell Death in Cells Exposed to 872 MHz Radiofrequency Radiation and Oxidants
Hoyto A et al. (2008): Radiofrequency radiation does not significantly affect ornithine decarboxylase activity, proliferation, or caspase-3 activity of fibroblasts in different physiological conditions
Takashima Y et al. (2006): Effects of continuous and intermittent exposure to RF fields with a wide range of SARs on cell growth, survival, and cell cycle distribution
Hirose H et al. (2006): Phosphorylation and gene expression of p53 are not affected in human cells exposed to 2.1425 GHz band CW or W-CDMA modulated radiation allocated to mobile radio base stations
Capri M et al. (2004): In vitro exposure of human lymphocytes to 900 MHz CW and GSM modulated radiofrequency: studies of proliferation, apoptosis and mitochondrial membrane potential