研究のタイプ: 医学/生物学の研究 (experimental study)

[妊娠中の超高周波電磁界放射はラット子孫の赤血球での小核発生の増加をもたらす] med./bio.

Ultra high frequency-electromagnetic field irradiation during pregnancy leads to an increase in erythrocytes micronuclei incidence in rat offspring.

掲載誌: Life Sci 2006; 80 (1): 43-50

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研究目的(著者による)

This study should investigate in rats whether 1.) radiofrequency electromagnetic fields could induce chromosomal damage in erythocytes of rat offspring whose mothers were exposed during pregnancy and 2.) imbalances in free radical metabolism of rat offspring liver and blood occurs.

詳細情報

The exposure group consisted of six adult pregnant rats (90-110 days old, 200-250 grams) and the control group of four animals.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 834 MHz
ばく露時間: repeated daily exposure, 8.5 h/day, throughout pregnancy

ばく露1

主たる特性
周波数 834 MHz
タイプ
  • electromagnetic field
ばく露時間 repeated daily exposure, 8.5 h/day, throughout pregnancy
Additional information vertical polarisation
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
  • analogue, in test mode, with stabilised power supply
Distance between exposed object and exposure source 29.5 cm
チャンバの詳細 Faraday cage (101.5 x 64 x 38 cm) made of 0.5-cm mesh
ばく露装置の詳細 The rats were housed in individual Plexiglas cages (40.5 x 33.5 x 17.5 cm) that were placed for exposure 29.5 cm away from the mobile phone antenna in its maximum radiation direction.
Sham exposure A sham exposure was conducted.
Additional information The Faraday cage containing the control animal was kept 40.5 cm away from the cage containing the exposure source. Both cages were placed in a wooden rack, and their places were switched every other day.
パラメータ
測定量 種別 Method Mass 備考
電力 0.6 W peak - - -
電界強度 40 V/m - 測定値 - 26.8-40 V/m
磁界強度 100 mA/m - 測定値 - 70-100 mA/m
電力密度 0.4 mW/cm² mean 測定値 - 0.2-0.4 mW/cm²
SAR 1.23 W/kg - 計算値 - 0.55-1.23 W/kg

Reference articles

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
  • blood, liver
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

A statistically significant increase in micronuclei occurrence was observed in the irradiated group.
No significant differences were found in any oxidative parameter of offspring plasma and liver. Additionally, the average number of pups in each litter has not been significantly altered.
These data suggest that radiofrequency electromagnetic field is able to induce a genotoxic response in hematopoietic tissue during the embryogenesis. An imbalance in free radicals does not seem to play an important role in its genesis.

研究の種別:

研究助成

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