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To study the biological effect of 1763 MHz radiofrequency exposure from mobile phone on changes in cell cycle, DNA damage, stress response, and gene expression in immortalized mouse auditory hair cells.
cell cycle, DNA damage, stress response, and gene expression
分子生合成: stress response: gene expression (Applied Biosystems 1700 full genome expression mouse microarray) and protein expression (heat shock proteins Hsp27, Hsp70, Hsp90, and phosphorylated forms of JNK mitogen-activated protein kinase, p38 MAP kinase, and extracellular signal-regulated MAP kinase; Western blot)
The data show no evidence of the induction of cellular responses, including cell cycle distribution, DNA damage, stress response and gene expression, after 1763 MHz radiofrequency exposure at an SAR of 20 W/kg in immortalized mouse auditory hair cells.