研究のタイプ: 医学/生物学の研究 (experimental study)

[ラットの腎臓の発達に対する携帯電話電磁界への出生前ばく露の影響] med./bio.

The effect of exposure of rats during prenatal period to radiation spreading from mobile phones on renal development.

掲載誌: Ren Fail 2015; 37 (2): 305-309

この研究は、妊娠したSDラットばく露群と無ばく露対照群に分け、ばく露群には、900MHz電磁界ばく露妊娠第1日目から20日間継続し、胎仔の腎臓組織組織病理学的変化、アポトーシス血清中の尿素クレアチニン、電解質のレベルを調べた。その結果、ばく露群の腎臓組織では、軽度の充血と尿細管欠損、ボーマン嚢の拡張が見られた;腎尿細管細胞のアポトーシスに関する染色反応が対照群に比べ、ばく露群で強く見られた、と報告している。

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研究目的(著者による)

The effects of prenatal exposure of rats to a 900 MHz electromagnetic field on the development of kidneys should be investigated.

詳細情報

Pregant rats were either exposed to the electromagnetic field or not exposed (n=3 each). The offspring from exposed rats was assigned to the exposure group (group 1, n=7) and the offspring from unexposed rats was assigned to the control group (group 2, n=7). After 60 days (remark EMF-Portal: 60 days after start or end of exposure or after birth? reference not clear), young animals were killed and investigated.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 20 days during pregnancy

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 20 days during pregnancy
Modulation
Modulation type pulsed
Pulse width 577 µs
Repetition frequency 217 Hz
Additional information

simulation of GSM signal, talking mode

ばく露装置
ばく露の発生源/構造
  • antenna
チャンバの詳細 cages
ばく露装置の詳細 a generator with an external antenna placed closely and centrally under the cages
パラメータ
測定量 種別 Method Mass 備考
電力 2 W peak - - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Mild congestion and renal tubule defects as well as a dilatation of Bowman's capsule and increased apoptosis were observed in the kidney tissues of rats in the exposure group compared to the control group. However, these changes were not statistically significant.
The only significant result was an increased potassium level in exposed rats compared to the control group.
The authors conclude that prenatal exposure of rats to a 900 MHz electromagnetic field might have an effect on the renal development.

研究の種別:

研究助成

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