1800 MHz radiofrequency (mobile phones, different Global System for Mobile communication modulations) does not affect apoptosis and heat shock protein 70 level in peripheral blood mononuclear cells from young and old donors
[1800 MHz Hochfrequenz (Mobiltelefone, verschiedene GSM-Modulationen) hat keinen Einfluss auf Apoptose und den Level des Hitzeschock-Proteins HSP70 in peripheren mononukleären Blut-Zellen junger und alter Spender]
Capri M, Scarcella E, Bianchi E, Fumelli C, Mesirca P, Agostini C, Remondini D, Schuderer J, Kuster N, Franceschi C, Bersani F
Veröffentlicht in: Int J Radiat Biol 2004; 80 (6): 389-397
The exposure set-up consisted of two single-mode resonator cavities equipped with a fan and field sensors and placed within a CO2 incubator. Exposure and sham conditions were blindly assigned to the two waveguides by the computer-controlled signal unit. Field strengths, temperatures and fan currents as well as all commands were continuously logged. The difference in air temperature between the exposed and sham waveguide monitored with accurate Pt100 probes was less than 0.1°C.
Six 35-mm Petri dishes were exposed in each waveguide resonator with a dish holder placing them exactly in the H-field maximum of the standing wave. The system enabled the exposure of monolayers of cells with a non-uniformity of SAR of less than 30% (SD).
Sham and RF exposures were performed immediately after cell seeding with or without dRib treatment. The maximum temperature load for the exposed cells due to absorption was below 0.04°C. Simulations of the temperature distribution in the Petri dish showed that hot spots in the cell medium could be excluded.
Field, SAR and temperature characterizations were performed with numerical methods (FDTD) and were experimentally verified using the near-field scanner DASY3 equipped with dosimetric field and temperature probes. An uncertainty and variation analysis resulted in an absolute uncertainty of 20% for the SAR assessment and in variations in SAR for the cells of 29%, caused by the non-uniformity of the SAR distribution and other variations that could occur between different experiments.