この実験研究は、50 GHz電磁界がWistar系の雄ラットの生殖系に及ぼす影響を調べた。生後60日の動物を2群（ばく露群、擬似ばく露群）に分け、換気穴付きプレキシガラス製容器内に拘束して、継続的に一日2時間ずつ45日間、一定のSAR 8.0×10-4W/kgでのばく露、または擬似ばく露を行った。ばく露後屠殺して採取した精液において、擬似ばく露群に比較してばく露群では、スーパーオキシドディスムターゼ（SOD）、グルタチオンペルオキシダーゼ（GPx）の有意な低下（p≦0.05）、カタラーゼの有意な増加（p < 0.02）、ヒストンキナーゼの平均活性の有意な低下（p < 0.016）、アポトーシスの増加（p < 0.004）などが観察されたと報告している。
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To study the effects of 50 GHz microwave electromagnetic fields on the reproductive system of male rats.
12 rats were divided into one exposure group (6 animals) and one sham exposure group.
The investigated parameters "histone kinase" and "cell cycle" are correlated to each other.
|ばく露時間||continuous for 2 h/day on 45 days|
|ばく露装置の詳細||two rats in a 31 cm x 9.2 cm x 8.5 cm Plexiglas cage, cage placed in an exposure chamber lined with radar absorbing material, horn antenna place beside the long side of the cage|
|Sham exposure||A sham exposure was conducted.|
The data showed that prolonged exposure to the 50 GHz electromagnetic field may decrease the enzyme activities of histone kinase, glutathione peroxidase and superoxide dismutase. On the other hand, the enzyme activity of catalase and the amount of cells in apoptosis phase were increased in the exposed group. Moreover, it was confirmed that a decrease in cells in G2 phase-M phase (mitosis phase) is directly related to histone kinase enzyme activity. The authors suggest that a reduction or an increase in enzyme activities of antioxidants and histone kinase, and the levels in cell cycle observed under these experimental conditions may be related to an overproduction of reactive oxygen species under microwave exposure.
The authors conclude that these irradiations may have a significant effect on the reproductive system of male rats, which may be an indication of male infertility.