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To study the effects of prenatal (in utero) exposure in mice to WiFi signals on development and function of immune cells.
The development of the immune system begins during embryogenesis, continues through fetal life, and is followed by a postnatal maturation period lasting several weeks in mice. All these phases are highly susceptible to the action of several noxious agents.
Pregnant mice were divided into three groups (n=16 per group): 1.) cage control, 2.) sham exposed and 3.) exposed. Exposure started five days after mating and ended one day before the expected delivery. The offspring was examined at the age of 5 weeks and 26 weeks. At every time point, one male and one female pup from each dam were sacrificed to perform immunological analyses.
Modulation type: pulsed
ばく露時間: continuous for 2 h/day on 14 consecutive days (starting 5 days after mating, ending 1 day before expected delivery)
|チャンバの詳細||mice restrained in transparent cylindrical polymethyl-methacrylate jigs with the posterior part on the side of the field origin and maintained with the caudal axis parallel to the direction of field propagation|
|ばく露装置の詳細||two identical 120 cm long TEM cells; signal generated by commercial WiFi access point connected to a notebook via LAN and communicating with a PC using single channel transmission with channel 11; signal directly taken from the access point; daily clockwise rotation of the eight pregnant mice inside each of the two TEM cells used; temperature regulated; mice positioned at the two areas of maximum E-field (4 mice/area), two above and two under each of the two septums|
|Sham exposure||A sham exposure was conducted.|
|SAR||4 W/kg||average over mass||測定値および計算値||whole body||-|
No effects due to exposure to WiFi signals during pregnancy on mating success, number of newborns per dam and body weight of offspring at birth were found.
The results showed no exposure-related effects on the number and proliferation as well as on the cell differentiation in the thymus and the spleen at both time points. Observed differences were due to age and/or gender.
In summary, these results do not support the hypothesis that in utero-exposure to a WiFi signal has detrimental effects on the development of immune cells in mice.